Evidence map›Paper›PMID 42358794›Full record

ArticleChemical & biomedical imaging2026

Scalable Synthesis of Calcium Fluoride Nanoparticles as a Novel Ultrasound Contrast Agent for Imaging Tumor Targeted Delivery of Therapeutics.

Suresh Thangudu, Arutselvan Natarajan, Sourabh Mehta, Kireeti Phani Devarakonda, Tarik F Massoud, Ramasamy Paulmurugan

Abstract read
In one paragraph

Article in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Suresh ThanguduCanary Center for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine, Palo Alto, California 94304, United States.
Arutselvan NatarajanCanary Center for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine, Palo Alto, California 94304, United States.ORCID https://orcid.org/0000-0002-9958-2623
Sourabh MehtaCanary Center for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine, Palo Alto, California 94304, United States.
Kireeti Phani DevarakondaCanary Center for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine, Palo Alto, California 94304, United States.
Tarik F MassoudCanary Center for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine, Palo Alto, California 94304, United States.ORCID https://orcid.org/0000-0002-9694-1408
Ramasamy PaulmuruganCanary Center for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine, Palo Alto, California 94304, United States.ORCID https://orcid.org/0000-0001-7155-4738

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasound (US) imaging is one of the most widely used noninvasive diagnostic techniques in clinical practice due to its safety, real-time capability, and cost-effectiveness. However, traditional B-mode imaging provides limited information with low sensitivity. Recently microbubble (MB)-based contrast agents have been employed to enhance contrast signals while also facilitating the imaging of molecular targets in target tissues or pathological locations. Currently available MBs face several limitations, including large size (typically 1-10 μm), limited ability to penetrate beyond blood vessels, poor

Indexed as

biocompatibleCaF2 nanoparticlesfunctional propertiesnanocarrierscalable fabricationtherapeutic deliveryultrasound contrastultrasound contrast imaging

Identifiers

PMID42358794
PMCPMC13291996

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.