Evidence map›Paper›PMID 42358773›Full record

ArticleChemical & biomedical imaging2026

Brighter NIR Bioluminescence System for Mammalian Cell Bioimaging Based on Engineered Railroadworm Luciferase and 6'-Aminoluciferin Analogues.

Gabriel F Pelentir, Vanessa R Bevilaqua, Michio Kakiuchi, Takashi Hirano, Vadim R Viviani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriel F PelentirGraduate Program of Biotechnology, Federal University of São Carlos (UFSCar), São Carlos 13565-905, SP, Brazil.
Vanessa R BevilaquaBiomaterials Laboratory, Medical and Health Sciences Faculty, Pontifical University Catholic of São Paulo (PUC-SP), Sorocaba 18060-030, SP, Brazil.
Michio KakiuchiDepartment of Engineering Science, Graduate School of Informatics and Engineering, The University of Electro-Communications, Chofu, Tokyo 182-8585, Japan.
Takashi HiranoDepartment of Engineering Science, Graduate School of Informatics and Engineering, The University of Electro-Communications, Chofu, Tokyo 182-8585, Japan.ORCID https://orcid.org/0000-0002-1369-9047
Vadim R VivianiGraduate Program of Biotechnology, Federal University of São Carlos (UFSCar), São Carlos 13565-905, SP, Brazil.ORCID https://orcid.org/0000-0001-5558-9199

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Luciferases have been extensively used as reporter genes for bioimaging purposes. For bioimaging in live animals, however, far-red- and NIR-emitting systems are better suited. Despite many efforts to develop such NIR-emitting systems, currently only a few systems have been commercialized, including AkaLuc/akalumine, which emits at ∼650 nm. Departing from the natural red-emitting luciferase of

Indexed as

bioimagingbiophotonicsfar-red bioluminescenceluciferin amino analoguesNIR bioluminescence

Identifiers

PMID42358773
PMCPMC13291975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.