Evidence map›Paper›PMID 42358727›Full record

ArticleJACS Au2026

Catalyst-Controlled Regiodivergent C-H Olefination of Furanyl Carbamates through a Rational Approach.

François Richard, Morgan Languet, Cora Escande de Messières, Ahmed M Zaitoun, Alexandre Dupas, Xacobe C Cambeiro, Janine Cossy, Stellios Arseniyadis

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In one paragraph

Article in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

François RichardQueen Mary University of London, Department of Chemistry, Mile End Road, London E1 4NS, UK.ORCID https://orcid.org/0000-0003-4757-7029
Morgan LanguetESPCI Paris - PSL, 10 Rue Vauquelin, Paris 75005, France.
Cora Escande de MessièresQueen Mary University of London, Department of Chemistry, Mile End Road, London E1 4NS, UK.
Ahmed M ZaitounUniversity of Greenwich, School of Science, Central Ave, Chatham ME4 4TB, UK.
Alexandre DupasESPCI Paris - PSL, 10 Rue Vauquelin, Paris 75005, France.
Xacobe C CambeiroUniversity of Greenwich, School of Science, Central Ave, Chatham ME4 4TB, UK.ORCID https://orcid.org/0000-0002-7365-7201
Janine CossyESPCI Paris - PSL, 10 Rue Vauquelin, Paris 75005, France.ORCID https://orcid.org/0000-0001-8746-9239
Stellios ArseniyadisQueen Mary University of London, Department of Chemistry, Mile End Road, London E1 4NS, UK.ORCID https://orcid.org/0000-0001-6831-2631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selective functionalization of heteroarenes remains a central challenge in synthetic organic chemistry, given their widespread presence in natural products and pharmacologically active molecules. Although numerous strategies exist for the olefination of five-membered heteroarenes, few enable precise control over regioselectivity. Herein, we report a DFT-supported, catalyst-controlled C-H olefination of cyclic dienol carbamates that allows regioselective access to either C3- or C5-substituted heteroarenes. This strategy provides a rational and versatile platform for achieving positional selectivity in heteroarene functionalization.

Indexed as

catalyst controlC−H activationDFTfuranolefinationpyrroleregiodivergentrhodium catalysisthiophene

Identifiers

PMID42358727
PMCPMC13291970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.