Evidence map›Paper›PMID 42358708›Full record

ArticleJACS Au2026

Programmable Hierarchical Assembly of Atomically Precise Metal Nanoclusters Using Supra-Amphiphilic Nucleic Acids.

Gaoang Zhou, Siyuan Zhang, Yan Zhou, Bingjie Yan, Mulin Duan, Haoran Zheng, Liqi Zhou, Shihua Luo, Jianlei Shen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gaoang ZhouState Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Siyuan ZhangState Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Yan ZhouState Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Bingjie YanState Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Mulin DuanState Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Haoran ZhengState Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Liqi ZhouInstitute of Materiobiology, College of Sciences, Shanghai University, Shanghai 200444, China.
Shihua LuoDepartment of Traumatology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.
Jianlei ShenState Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID https://orcid.org/0000-0001-6386-5640

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amphiphilic nucleic acids enable programmable supramolecular assembly toward functional nanosystems, yet their typical construction via the covalent conjugation of hydrophobic groups limits architectural versatility. Achieving noncovalent amphiphilic nucleic acid architectures remains a significant challenge. Here, we report a strategy to assemble supra-amphiphilic nucleic acids through noncovalent interactions. The building blocks are partially phosphorothioate-modified single-stranded DNA and hydrophobic, atomically precise gold nanoclusters (Au NCs). The assembly is driven by hydrophobic contacts between nucleobases and the ligand shell of the Au NCs and coordination between the phosphorothioate backbone and the metal core. By precisely modulating the length of the hydrophilic DNA segment, these supra-amphiphiles self-assemble in the presence of Mg

Indexed as

DNA origamihierarchical assemblymetal nanoclustersingle-stranded DNAsupra-amphiphiles

Identifiers

PMID42358708
PMCPMC13291876

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.