Evidence map›Paper›PMID 42358605›Full record

ArticleFrontiers in aging neuroscience2026

Sustained attention in dementia with Lewy bodies: a task-based fMRI study.

Davide Braghittoni, Greta Venturi, Lucia Guidi, Elettra Capogna, Giovanni Sighinolfi, Luca Baldelli, Giulia Amore, Chiara La Morgia, Luisa Sambati, Annalena Venneri and 3 more

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In one paragraph

Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

13 authors.

Davide Braghittoni *IRCCS Istituto delle Scienze Neurologiche di Bologna, Functional and Molecular Neuroimaging Unit, Bologna, Italy.
Greta Venturi *IRCCS Istituto delle Scienze Neurologiche di Bologna, Functional and Molecular Neuroimaging Unit, Bologna, Italy.
Lucia GuidiIRCCS Istituto delle Scienze Neurologiche di Bologna, Functional and Molecular Neuroimaging Unit, Bologna, Italy.
Elettra CapognaIRCCS Istituto delle Scienze Neurologiche di Bologna, Functional and Molecular Neuroimaging Unit, Bologna, Italy.
Giovanni SighinolfiIRCCS Istituto delle Scienze Neurologiche di Bologna, Functional and Molecular Neuroimaging Unit, Bologna, Italy.
Luca BaldelliDepartment of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
Giulia AmoreIRCCS Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, Italy.
Chiara La MorgiaDepartment of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
Luisa SambatiIRCCS Istituto delle Scienze Neurologiche di Bologna, U.O.C. Clinica Neurologica Rete Metropolitana (NeuroMet), Bologna, Italy.
Annalena VenneriDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Raffaele LodiIRCCS Istituto delle Scienze Neurologiche di Bologna, Functional and Molecular Neuroimaging Unit, Bologna, Italy.
Caterina Tonon *IRCCS Istituto delle Scienze Neurologiche di Bologna, Functional and Molecular Neuroimaging Unit, Bologna, Italy.
Micaela MitoloIRCCS Istituto delle Scienze Neurologiche di Bologna, Functional and Molecular Neuroimaging Unit, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Patients with Dementia with Lewy Bodies (DLB) typically experience attentional deficits. Understanding these deficits and the underlying neural correlates is crucial as sustained attention supports higher level cognitive functions. The objective of this study was to investigate the patterns of brain connectivity during a functional magnetic resonance imaging (fMRI) sustained attention task in a DLB group compared with healthy controls (HC). Methods: In this study, 30 DLB patients and 25 HC underwent a comprehensive neuropsychological assessment and a brain 3T MRI protocol that included a high-resolution structural sequence (T1-w 3D MPRAGE) and a task-based fMRI study using an auditory Psychomotor Vigilance Task (PVT). Results: DLB patients performed worse in neuropsychological tests mainly related to the visuospatial domain and had poorer performance than HC on sustained attention (i.e., PVT) in terms of lapses and longer response times. Moreover, during the PVT, the DLB group exhibited significantly lower activation in the precuneus, intracalcarine cortex, angular gyrus and cuneus, regions implicated in sustained attention. Discussion: Overall, the identification of a distinct pattern of brain activity related to attention impairment in DLB patients offers opportunities for the development of tailored cognitive stimulation treatments.

Indexed as

Dementia with Lewy bodiesfunctional MRIprecuneuspsychomotor vigilance tasksustained attention

Identifiers

PMID42358605
PMCPMC13290862

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