Evidence map›Paper›PMID 42358563›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Subjective cognitive complaints and decline among aging individuals with prior repetitive head impact exposure.

Anna Aaronson, Monica T Ly, Yorghos Tripodis, Caroline Altaras, Steven Lenio, Chad W Farris, Christopher J Nowinski, Maureen K O'Connor, Brett M Martin, Joseph N Palmisano and 9 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Anna AaronsonBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Monica T LyBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Yorghos TripodisBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Caroline AltarasBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Steven LenioBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Chad W FarrisBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Christopher J NowinskiBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Maureen K O'ConnorBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Brett M MartinBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Joseph N PalmisanoBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Rachel L NoshenyDepartment of Psychiatry and Behavioral Sciences University of California San Francisco San Francisco California USA.
Katherine A GiffordDepartment of Anatomy and Neurobiology Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Eric G SteinbergBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Katherine W TurkBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Andrew E BudsonBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Thor D SteinBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Ann C McKeeBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Jesse MezBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.
Michael L AloscoBoston University Alzheimer's Disease Research Center and CTE Center Boston University Chobanian & Avedisian School of Medicine Boston Massachusetts USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSubjective cognitive complaints (SCC) can precede Alzheimer's disease and related dementias. SCC in the absence of objective impairment is termed subjective cognitive decline (SCD). This study aimed to characterize SCC and SCD among a sample of aging individuals with and without prior repetitive head impact (RHI) exposure, the former of whom are at risk for chronic traumatic encephalopathy (CTE).

methodsRHI-exposed (

resultsRHI exposure was associated with greater self- and informant-reported SCC and with over four-fold increased odds of SCD among cognitively unimpaired participants (odds ratio = 4.10, DISCUSSION: Among RHI-exposed individuals, SCC align with objective cognitive performance. SCD warrants investigation as potential early indicator of RHI-related neuropathologies.

Indexed as

Alzheimer's diseasechronic traumatic encephalopathydementiamild cognitive impairmentneurodegenerative diseaserepetitive head impactssubjective cognitive complaintssubjective cognitive declinetraumatic encephalopathy syndrome

Identifiers

PMID42358563
PMCPMC13290649

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.