Evidence map›Paper›PMID 42358399›Full record

ArticleFrontiers in psychiatry2026

Tracking the longitudinal course of physiologic and mental health functioning among individuals in substance use disorder treatment.

Wendy Insalaco, Charlotte Clapham, Brett Gelino, Jami Mayo Barney, Brianna Billings, Jennifer D Ellis, J Gregory Hobelmann, Andrew S Huhn, Vadim Zipunnikov, Jill A Rabinowitz

Abstract read
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In one paragraph

Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wendy InsalacoAshley Addiction Treatment, Havre de Grace, MD, United States.
Charlotte ClaphamDepartment of Biostatistics, Johns Hopkins University, Baltimore MD, United States.
Brett GelinoDepartment of Psychiatry, Robert Wood Johnson Medical School, Piscataway, NJ, United States.
Jami Mayo BarneyAshley Addiction Treatment, Havre de Grace, MD, United States.
Brianna BillingsAshley Addiction Treatment, Havre de Grace, MD, United States.
Jennifer D EllisDepartment of Psychiatry and Behavioral Services, Johns Hopkins University, Baltimore, MD, United States.
J Gregory HobelmannAshley Addiction Treatment, Havre de Grace, MD, United States.
Andrew S HuhnDepartment of Psychiatry and Behavioral Services, Johns Hopkins University, Baltimore, MD, United States.
Vadim ZipunnikovDepartment of Biostatistics, Johns Hopkins University, Baltimore MD, United States.
Jill A RabinowitzDepartment of Psychiatry, Robert Wood Johnson Medical School, Piscataway, NJ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Mental health monitoring is crucial to long-term recovery in substance use disorder (SUD) treatment; however, little is known about how changes in physiological indicators align with changes in self-reported mental health over time. Methods: We examined longitudinal associations of resting heart rate (RHR) and heart rate variability (HRV) collected via a WHOOP® photoplethysmography device with self-reported stress, anxiety, and depressive symptoms among individuals in SUD treatment. Participants ( Results: Linear regression results indicated favorable changes in mental health and/or physiologic metrics, with notable heterogeneity in concurrent subject-level trends. Among participants with decreased RHR (better physiological functioning), 39% ( Discussion: Concurrent changes in physiologic and mental health metrics during the first month of treatment varied across participants. These findings highlight the importance of integrating subjective mental health measures with physiological indicators to capture clinically relevant change during early SUD treatment.

Indexed as

Heart rate variability (HRV)photoplethysmography (PPG)recoveryresting heart rate (RHR)substance use disorder (SUD)wearable

Identifiers

PMID42358399
PMCPMC13290847

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.