Evidence map›Paper›PMID 42358248›Full record

SynthesisFrontiers in microbiology2026

The dual role of Actinobacteria in aquaculture: a systematic review of metabolic benefits and detrimental effects.

Claudia Zuluaga-Quintero, Luis Eduardo Diaz Barrera, Luisa Villamil

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Claudia Zuluaga-QuinteroDoctoral Program of Biosciences, School of Engineering, Universidad de la Sabana, Chía, Colombia.
Luis Eduardo Diaz BarreraIndependent Researcher, Bogota, Colombia.
Luisa VillamilDoctoral Program of Biosciences, School of Engineering, Universidad de la Sabana, Chía, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Actinobacteria are ubiquitous and metabolically versatile members of aquatic microbiomes, yet their roles in aquaculture remain under-characterized compared with other microbial groups. This systematic review synthesizes current evidence on their functional duality in farmed fish systems, integrating both metabolic benefits and detrimental effects. Methods: Studies describing Actinobacterial isolates with at least one laboratory validation were systematically collected and critically evaluated. Methodological approaches were examined to distinguish Results: Only a minority of studies progressed beyond Discussion: These outcomes appear highly context-dependent and reflect ecological adaptations rather than intrinsic hazards. By consolidating evidence on both beneficial and detrimental traits, this review highlights the need for genome-resolved taxonomy and ecologically informed screening pipelines to guide the safe and effective integration of Actinobacteria into aquaculture.

Indexed as

Actinobacteriaaquaculture microbiomebiocontrol agentsoff-flavor compoundsquorum sensing inhibitionstreptomyces

Identifiers

PMID42358248
PMCPMC13293482

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.