Evidence map›Paper›PMID 42358059›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2026

HIV Seroprevalence, Incidence, and Viral Suppression Among Ugandan Female Bar Workers: A Population-Based Study.

Xinyi Feng, Gertrude Nakigozi, Eshan U Patel, Caitlin E Kennedy, Slisha Shrestha, Fred Nalugoda, Godfrey Kigozi, Robert Ssekubugu, Larry W Chang, Andrea L Wirtz and 8 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Xinyi FengDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
Gertrude NakigoziRakai Health Sciences Program, Kalisizo, Uganda.
Eshan U PatelDepartment of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD.
Caitlin E KennedyDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Slisha ShresthaDepartment of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD.
Fred NalugodaRakai Health Sciences Program, Kalisizo, Uganda.
Godfrey KigoziRakai Health Sciences Program, Kalisizo, Uganda.
Robert SsekubuguRakai Health Sciences Program, Kalisizo, Uganda.
Larry W ChangRakai Health Sciences Program, Kalisizo, Uganda.
Andrea L WirtzDepartment of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD.
Arthur G FitzmauriceDivision of Global HIV & TB, Global Health Center, U.S. Centers for Disease Control and Prevention, Kampala, Uganda; and.
Hadijja NakawooyaRakai Health Sciences Program, Kalisizo, Uganda.
Grace KigoziRakai Health Sciences Program, Kalisizo, Uganda.
Ronald M GaliwangoRakai Health Sciences Program, Kalisizo, Uganda.
Steven J ReynoldsDivision of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD.
Joseph KagaayiRakai Health Sciences Program, Kalisizo, Uganda.
Aaron A R TobianDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
M Kate GrabowskiDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0002-4451-3436

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
International Center for Excellence in Research (ICER) in Uganda: Impact of ARVsZIAAI001040 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI REYNOLDS, STEVEN · 2009 to 2025
$23.5M
Circumcision: HIV/STIs and behaviors in a RCT and post-RCT surveillance; RakaiU01AI075115 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAY, RONALD H · 2007 to 2011
$9.3M
Epidemiology and Impact of the HIV, NCD, and Urbanization Syndemic in AfricaR01HL152813 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CHANG, LARRY WILLIAM · 2021 to 2025
$7.8M
ARV effects on HIV epidemiology &behaviors Rakai UgandaR01HD050180 · NICHD · JOHNS HOPKINS UNIVERSITY · PI WAWER, MARIA J · 2005 to 2009
$7.8M
Structural and Social Transitions Among Adolescents in Rakai (SSTAR)R01HD091003 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SANTELLI, JOHN S. · 2017 to 2021
$3.7M
T-cell depletion and maintenance of the HIV-1 latent reservoir in distinct tissue compartmentsR01DK131926 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI Melissa Laird Smith, AARON A TOBIAN · 2022 to 2026
$3.6M
The role of penile bacteria and inflammation in HIV susceptibility; Rakai, UgandaR01AI123002 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI LIU, CINDY · 2016 to 2020
$3.3M
Enhanced Provision of Male Circumcision for HIV Prevention, Rakai, UgandaU01AI100031 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAY, RONALD H · 2012 to 2014
$3.2M
Evaluating Demand Generation (Stylish Man) for HIV/Family Planning Services RakaiR01AI114438 · NIAID · JOHNS HOPKINS UNIVERSITY · PI WAWER, MARIA J · 2014 to 2017
$3.0M
Genital Anaerobes, Inflammation and HIV Risk; RakaiR01AI087409 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAY, RONALD H, PRICE, LANCE BRADLEY · 2010 to 2012
$2.5M
Long-term impact of universal treatment and dolutegravir on population HIV virologic and incidence outcomes in Africa: The LONGVIEW StudyR01AI155080 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRABOWSKI, MARY KATHRYN · 2021 to 2024
$2.5M
Center for AIDS Research, Johns Hopkins University P30AI094189Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases U01AI075115, R01AI087409, U01AI100031, R01AI110324, R01AI114438, K25AI114461, R01AI123002, R01AI128779, R01AI143333, R21AI145682, R01AI155080, ZIAAI001040FIC NIH HHS D43 TW009578FIC NIH HHS D43TW009578, D43TW010557FIC NIH HHS D43 TW010557Intramural NIH HHS ZIA AI001040National Institute of Child Health and Human Development R01HD050180, R01HD070769, R01HD091003NHLBI NIH HHS R01 HL152813NHLBI NIH HHS R01HL152813NIAID NIH HHS K25 AI114461NIAID NIH HHS P30 AI094189NIAID NIH HHS R01 AI087409NIAID NIH HHS R01 AI110324NIAID NIH HHS R01 AI114438NIAID NIH HHS R01 AI123002NIAID NIH HHS R01 AI128779NIAID NIH HHS R01 AI143333NIAID NIH HHS R01 AI155080NIAID NIH HHS R21 AI145682NIAID NIH HHS U01 AI075115NIAID NIH HHS U01 AI100031NICHD NIH HHS R01 HD050180NICHD NIH HHS R01 HD070769NICHD NIH HHS R01 HD091003NIDDK NIH HHS R01 DK131926NIDDK NIH HHS R01DK131926
6 · The paper itself

Abstract

introductionPrior studies have shown that some female bar workers (FBWs) may engage in sex work in Africa. However, population-level data on the HIV burden among FBWs in African settings are limited.

methodsData from 5 survey rounds (2011-2020) of the Rakai Community Cohort Study, a population-based HIV surveillance cohort in 36 inland agrarian/trading communities (HIV prevalence ∼12%) and 4 Lake Victoria fishing communities (∼40%) in southern Uganda, were analyzed. Women reporting bar work as a primary or secondary occupation were identified and compared with non-FBWs. Primary outcomes included HIV seropositivity, incident HIV infection, viral suppression (<200 copies/mL) among women with HIV, and population prevalence of viremia. Prevalence ratios and incidence rate ratios were estimated using Poisson regression with 95% confidence intervals (CIs).

resultsAmong 23,556 female participants contributing 52,708 person-visits, 1205 (5.1%) self-identified as FBWs, who had significantly higher baseline HIV seroprevalence than non-FBWs (51.9% vs. 18.5%; prevalence ratio = 2.81; 95% CI = 2.64 to 2.95). There were 356 incident HIV infections over 39,228 person-years. HIV incidence among FBWs was 2.49 per 100 person-years compared with 0.87 among non-FBWs (age-adjusted incidence rate ratio = 3.64; 95% CI = 2.33 to 5.42). Although HIV viral suppression was similar among participants living with HIV regardless of FBW status, the population prevalence of HIV viremia was 1.69 times higher among FBWs (95% CI = 1.38 to 2.08). Among 179 HIV-seronegative FBWs surveyed during 2018-2020, 79.9% (143/179) were aware of preexposure prophylaxis, whereas only 13.4% (24/179) had ever used it, and 2.8% (5/179) were current users.

conclusionsFBWs in Uganda experience a substantially higher HIV burden and acquisition risk compared with the general population. Prevention strategies tailored to the occupational context of bar work, including prioritization of HIV service delivery and access to oral and long-acting injectable preexposure prophylaxis, may substantially reduce HIV incidence among FBWs and their sexual partners.

Indexed as

HIV InfectionsHIV SeroprevalenceAdolescentAdultCohort StudiesFemaleHumansIncidenceMiddle AgedPrevalenceUgandaViral LoadYoung Adultfemale bar workerfemale sex workerHIVHIV incidencekey populationpreexposure prophylaxisUganda

Identifiers

PMID42358059
PMCPMC13566408

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