Evidence map›Paper›PMID 42357736›Full record

ArticleVeterinary sciences2026

The Influence of Age on the Pharmacokinetics of Enrofloxacin and Ciprofloxacin in Calves.

Orhan Corum, Murat Yuksel, Duygu Durna Corum, Elisa Escudero, Pedro Marín, Mario Giorgi, Halis Oguz, Erdinc Turk, Devran Coskun, Elena Badillo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Orhan CorumDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Hatay Mustafa Kemal, Hatay 31060, Türkiye.ORCID 0000-0003-3168-2510
Murat YukselDepartment of Obstetrics and Gyneacology, Faculty of Veterinary Medicine, University of Hatay Mustafa Kemal, Hatay 31060, Türkiye.
Duygu Durna CorumDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Hatay Mustafa Kemal, Hatay 31060, Türkiye.
Elisa EscuderoDepartment of Pharmacology, Faculty of Veterinary Medicine, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0002-4354-322X
Pedro MarínDepartment of Pharmacology, Faculty of Veterinary Medicine, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0003-4849-4452
Mario GiorgiDepartment of Veterinary Sciences, University of Pisa, San Piero a Grado, 56121 Pisa, Italy.
Halis OguzDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Selcuk, Konya 42031, Türkiye.
Erdinc TurkDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Hatay Mustafa Kemal, Hatay 31060, Türkiye.
Devran CoskunDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Siirt, Siirt 56100, Türkiye.
Elena BadilloDepartment of Pharmacology, Faculty of Veterinary Medicine, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0003-0888-4851
María Teresa YusteDepartment of Pharmacology, Faculty of Veterinary Medicine, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0002-9897-8140
Kamil UneyDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Selcuk, Konya 42031, Türkiye.ORCID 0000-0002-8674-4873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated age-related variations in the pharmacokinetics of enrofloxacin and its active metabolite, ciprofloxacin, in calves. This study was carried out on a total of 18 calves using a parallel pharmacokinetic design. Eighteen animals were assigned to three age groups, one, four, and eight months old, and received a single intravenous dose of 10 mg/kg enrofloxacin. Serial blood samples collected over 48 h were analyzed using high-performance liquid chromatography to determine plasma concentrations. In one-month-old calves, the pharmacokinetic parameters revealed a volume of distribution at steady state (V

Indexed as

agecattleciprofloxacinenrofloxacinintravenouspharmacokinetics

Identifiers

PMID42357736
PMCPMC13308158

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.