ArticleViruses2026
Beyond Infection: The Interplay of Salivary Human Herpesvirus 6, Stress, and Host Factors in Major Depressive Disorder.
Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Human Herpesvirus 6 (HHV-6) is a neurotropic virus associated with lifelong latency and stress-induced reactivation. Its role in major depressive disorder (MDD) remains unclear. This study investigated the association between HHV-6 infection and MDD and evaluated interaction effects with psychosocial and clinical factors. A cross-sectional study was conducted among 2403 university students in Thailand, including 52 participants with physician-diagnosed MDD and 2351 healthy controls. HHV-6 DNA was detected by quantitative polymerase chain reaction (qPCR) using saliva. Logistic regression and interaction analyses were performed. HHV-6 DNA was detected in 50.7% of participants. HHV-6 infection was not significantly associated with MDD (OR = 1.335, 95% CI: 0.766-2.328,
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