Evidence map›Paper›PMID 42357646›Full record

ReviewViruses2026

An Update on HIV Pre-Exposure Prophylaxis (PrEP) Among Women.

Tamara Barnett, Daniel Cloutier, Rafique Van Uum, Parsa Ebrahimpoor Mashhadi, Agustina Crespi, Hadeeka Tahir, Sajeela Rana, Carlee Giffen, Roya Haghiri-Vijeh, Mia J Biondi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tamara BarnettSchool of Nursing, York University, 301A 4700 Keele Street, Toronto, ON M3J 1P3, Canada.
Daniel CloutierSchool of Nursing, York University, 301A 4700 Keele Street, Toronto, ON M3J 1P3, Canada.
Rafique Van UumSchool of Nursing, York University, 301A 4700 Keele Street, Toronto, ON M3J 1P3, Canada.
Parsa Ebrahimpoor MashhadiSchool of Nursing, York University, 301A 4700 Keele Street, Toronto, ON M3J 1P3, Canada.ORCID 0009-0003-7130-0342
Agustina CrespiSchool of Nursing, York University, 301A 4700 Keele Street, Toronto, ON M3J 1P3, Canada.
Hadeeka TahirSchool of Nursing, York University, 301A 4700 Keele Street, Toronto, ON M3J 1P3, Canada.
Sajeela RanaSchool of Nursing, York University, 301A 4700 Keele Street, Toronto, ON M3J 1P3, Canada.
Carlee GiffenSchool of Nursing, York University, 301A 4700 Keele Street, Toronto, ON M3J 1P3, Canada.
Roya Haghiri-VijehSchool of Nursing, York University, 301A 4700 Keele Street, Toronto, ON M3J 1P3, Canada.ORCID 0000-0003-2462-5120
Mia J BiondiSchool of Nursing, York University, 301A 4700 Keele Street, Toronto, ON M3J 1P3, Canada.

Funding

York University Junior Faculty/Minor Research Grant
6 · The paper itself

Abstract

Globally, cis and trans women face increasing rates of HIV, yet the uptake of existing HIV prevention medications often fails to meet their specific needs. This review examines HIV pre-exposure prophylaxis (PrEP) use among cis and trans women, including adolescent girls and young women; newcomers and migrants; sex workers; women who use drugs; and women who have been incarcerated, acknowledging intersectionality exists between these groups. A review of peer-reviewed published literature was conducted, and findings specifically on oral PrEP were synthesized. This review highlights several key themes shaping women's engagement with PrEP, including barriers to initiation and discontinuation; public health messaging and promotion; the role of women's networks; intimate partner violence; interpersonal trust in relationships; and "seasons of risk," where temporary reductions in perceived risk may lead to discontinuation. Additional themes include preferred access points for PrEP, regional differences, and clinical implications for practice. Peer support and peer navigators emerge as important mechanisms for creating safe spaces that enhance trust and sustained PrEP use. Improving PrEP uptake and persistence among women requires a multifaceted, women-centred approach that addresses clinical, social, and structural barriers. Context-specific implementation remains critical to addressing diverse lived realities and strengthening HIV prevention outcomes globally.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisFemaleHumansAnti-HIV AgentsaccessHIVmedicationpre-exposure prophylaxis (PrEP)preventionwomen

Identifiers

PMID42357646
PMCPMC13307654

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.