ArticleViruses2026
Nationwide Detection and Molecular Characterization of Hepatitis E Virus RNA in Retail Pork Meat in Japan.
Masaharu Takahashi, Manri Kawakami, Yukihiro Sato, Tatsunori Nakano, Jun Inoue, Junichi Koyama, Hitoshi Mizuo, Tomoya Koda, Kazumi Yamasaki, Hiroshi Okano and 10 more
Abstract read
In one paragraphArticle in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
20 authors.
Masaharu TakahashiDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke 329-0498, Japan.ORCID 0000-0001-6888-9318 Manri KawakamiDepartment of Hepatology, Okayama Saiseikai General Hospital, Okayama 700-8511, Japan.
Yukihiro SatoDepartment of Internal Medicine, Kamiichi General Hospital, Nakaniikawa-gun 930-0391, Japan.
Tatsunori NakanoDepartment of Internal Medicine, Fujita Health University Nanakuri Memorial Hospital, Tsu 514-1295, Japan.ORCID 0000-0003-2682-3809 Jun InoueDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.ORCID 0000-0003-1171-7835 Junichi KoyamaDepartment of Internal Medicine, Kin-Ikyo Chuo Hospital, Sapporo 007-8505, Japan.
Hitoshi MizuoHokkaido Medical Checkup and Internal Medicine Clinic, Sapporo 060-0032, Japan.
Kazumi YamasakiClinical Research Center, NHO Nagasaki Medical Center, Omura 856-8562, Japan.
Hiroshi OkanoDepartment of Gastroenterology, Suzuka General Hospital, Suzuka 513-8630, Japan.
Akio MiyasakaDivision of Gastroenterology, Department of Internal Medicine, Iwate Medical University School of Medicine, Shiwa-gun 028-3694, Japan.
Shunji WatanabeDivision of Gastroenterology, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke 329-0498, Japan.ORCID 0000-0002-5449-6553 Norio IsodaDivision of Gastroenterology, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke 329-0498, Japan.
Tomofumi TakagiJCHO Sapporo Hokushin Hospital, Sapporo 004-8618, Japan.
Hiroshi OhnishiDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke 329-0498, Japan.ORCID 0000-0003-0247-5440 Putu Prathiwi PrimadharsiniDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke 329-0498, Japan.ORCID 0000-0001-7401-979X Shigeo NagashimaDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke 329-0498, Japan.ORCID 0000-0001-8944-713X Kazumoto MurataDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke 329-0498, Japan.ORCID 0000-0002-3419-6297 Hiroaki OkamotoDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke 329-0498, Japan.ORCID 0000-0003-0827-0964 Funding
Japan Agency for Medical Research and Development JP25fk0210132Japan Agency for Medical Research and Development JP26fk0210198
6 · The paper itselfAbstract
Hepatitis E virus (HEV) is a major zoonotic pathogen, with pigs serving as the principal animal reservoir. While consumption of raw or undercooked pig liver is a well-recognized risk factor, systematic data on HEV contamination in retail pork meat remain limited. In this study, 1546 retail pork samples collected from eight geographic regions across Japan were analyzed for HEV RNA using a validated nested RT-PCR method. Analytical sensitivity was determined using the World Health Organization (WHO) International Standard for HEV RNA, yielding a 95% limit of detection (LOD95) of 134 IU/g (95% CI: 105-193). Overall, 15 samples (1.0%) tested positive for HEV RNA, with no significant regional variation (0.4-1.8%;
Indexed as
Hepatitis EHepatitis E virusPork MeatRed MeatRNA, ViralAnimalsGenotypeHumansJapanPhylogenySwineSwine DiseasesRNA, Viralfoodborne transmissionhepatitis E virusJapanmolecular epidemiologynested RT-PCRpork meatzoonosis
Identifiers
PMID42357631
PMCPMC13307769
What OpenQuestion holds
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