Evidence map›Paper›PMID 42357617›Full record

ArticleViruses2026

A Pediatric Case of Rapidly Progressing Disseminated Human Adenovirus C1 Infection with Multiorgan Failure and Evidence of Intra-Host Variation.

William Otto, Lindsey Rickerman, Maria Deza Leon, Felicia Scaggs Huang, Krithivasan Sankaranarayanan, Christopher Dandoy, Daryl M Lamson, Adriana E Kajon

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

William OttoCincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Lindsey RickermanWadsworth Center, New York State Department of Health, Albany, NY 12208, USA.ORCID 0000-0003-1305-1870
Maria Deza LeonCincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Felicia Scaggs HuangCincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Krithivasan SankaranarayananWadsworth Center, New York State Department of Health, Albany, NY 12208, USA.
Christopher DandoyCincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-4001-9203
Daryl M LamsonWadsworth Center, New York State Department of Health, Albany, NY 12208, USA.ORCID 0000-0002-6497-917X
Adriana E KajonLovelace Biomedical Research Institute, Albuquerque, NM 87108, USA.ORCID 0000-0001-6499-9579

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A strain of human adenovirus type C1 was isolated from multiple anatomical compartments in a pediatric patient with late-onset Pompe disease. Over a period of 23 days from the appearance of fever and respiratory symptoms until death, disease progression was rapid with severe disseminated disease and complications that included respiratory distress, liver failure, cardiac dysfunction, and hemophagocytic lymphohistiocytosis. Detected viral DNAemia peaked at log

Indexed as

Adenoviruses, HumanAdenovirus Infections, HumanMultiple Organ FailureChild, PreschoolDisease ProgressionDNA, ViralFatal OutcomeGenetic VariationHigh-Throughput Nucleotide SequencingHumansMalePhylogenyDNA, Viraladenovirusdisseminated diseasehemophagocytic lymphohistiocytosisintra-host genetic variationiSNVnext generation sequencing

Identifiers

PMID42357617
PMCPMC13307845

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.