Beyond Chemodiversity: A General Biosynthetic Diversity Index for Plant Metabolic Architecture in Ecology, Evolutionary, and Bioprospection.

Davyson de Lima Moreira, Renato Crespo Pereira, Ygor Jessé Ramos

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Chemical Game Theory: Linking Metabolite Diversity, Biosynthetic Architecture, and Realized Payoffs.Molecules (Basel, Switzerland) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Davyson de Lima MoreiraResearch Institute of the Rio de Janeiro Botanical Garden, Rua Pacheco Leão 915, Jardim Botânico, Rio de Janeiro 22460-030, RJ, Brazil.ORCID 0000-0002-3060-0395

Renato Crespo PereiraDepartment of Marine Biology, Universidade Federal Fluminense, Campus do Valonguinho, Outeiro de São João Batista, s/n, Centro, Niterói 24020-141, RJ, Brazil.ORCID 0000-0001-7576-226X

Ygor Jessé RamosFarmácia da Terra Laboratory, Faculty of Pharmacy, Federal University of Bahia, Rua Barão de Jeremoabo, 147, Ondina, Salvador 40170-115, BA, Brazil.ORCID 0000-0003-4443-1008

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant chemical diversity is commonly assessed using abundance-based metrics that treat metabolites as independent components, although these approaches do not explicitly represent how compounds are organized across biosynthetic routes. Here, we present a proof-of-concept application of the General Biosynthetic Diversity Index (GBDI), a pathway-informed descriptor of plant chemical mixtures that integrates relative metabolite abundance with biosynthetic-route attribution. The index was evaluated using hypothetical mixtures and essential oil datasets from

Indexed as

Biosynthetic PathwaysPlantsBiological EvolutionEcologyOils, VolatilePlant LeavesOils, Volatilebiosynthetic pathwayschemical diversitygeneral biosynthetic diversity indexmetabolic architectureplant secondary metabolism

Identifiers

PMID42357583

DOI10.3390/molecules31122188

PMCPMC13304874

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.