Evidence map›Paper›PMID 42357315›Full record

ArticlePharmaceutics2026

Ocular Troxipide Nanosuspension Enhances Therapeutic Efficacy in an N-Acetylcysteine-Induced Dry Eye Model.

Hiroko Otake, Rie Tanaka, Fumihiko Ogata, Yosuke Nakazawa, Manju Misra, Kazutaka Kanai, Masanobu Tsubaki, Naoki Yamamoto, Naohito Kawasaki, Noriaki Nagai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroko OtakeFaculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-Osaka 577-8502, Osaka, Japan.
Rie TanakaFaculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-Osaka 577-8502, Osaka, Japan.
Fumihiko OgataFaculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-Osaka 577-8502, Osaka, Japan.ORCID 0000-0002-2755-8341
Yosuke NakazawaFaculty of Pharmaceutical Sciences, Doshisha Woman's College of Liberal Arts, 97-1, Minamihokotate, Kodo, Kyotanabe 610-0395, Kyoto, Japan.ORCID 0000-0002-2226-1944
Manju MisraDepartment of Pharmaceutics and Pharmacy Technology, L. M. College of Pharmacy, Navrangpura, Ahmedabad 380009, Gujarat, India.
Kazutaka KanaiDepartment of Small Animal Internal Medicine II, School of Veterinary Medicine, Kitasato University, 35-1 Higashi 23 Ban-Cho, Towada 034-8628, Aomori, Japan.ORCID 0000-0003-3690-2332
Masanobu TsubakiLaboratory of Pharmacotherapy, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, Sanuki 769-2193, Kagawa, Japan.ORCID 0000-0003-3129-2678
Naoki YamamotoUniversity Startup Promotion Center, Research Promotion Headquarters, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake 470-1192, Aichi, Japan.ORCID 0000-0002-9659-3204
Naohito KawasakiFaculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-Osaka 577-8502, Osaka, Japan.ORCID 0000-0002-9412-0868
Noriaki NagaiFaculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-Osaka 577-8502, Osaka, Japan.ORCID 0009-0007-1266-038X

Funding

Ministry of Education, Culture, Sports, Science and Technology of Japan 25K10101
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dry eyenanosuspensionocular drug deliverytear fluidtroxipide

Identifiers

PMID42357315
PMCPMC13306505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.