Evidence map›Paper›PMID 42356981›Full record

ReviewPolymers2026

Hydrogel-Based Sensors: Compositions, Fabrication, Sensing Mechanism, and Applications.

Hassanain Ali, Xiao-Feng Sun, Zeesham Ali, Ran Sun, Sihai Hu

Abstract readReview
In one paragraph

Review in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hassanain AliSchool of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an 710129, China.
Xiao-Feng SunSchool of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an 710129, China.ORCID 0000-0002-7012-467X
Zeesham AliCollege of New Materials and Nanotechnolgies, National University of Science and Technology MISIS, Moscow 119049, Russia.
Ran SunSchool of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an 710129, China.ORCID 0000-0002-4724-2504
Sihai HuSchool of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an 710129, China.

Funding

Key Research and Development Program of Shaanxi Province 2024NC-YBXM-233Science and Technology Program of Xi'an 2023NYGG0049Science and Technology Program of Xi'an 2024JH-NYYB-0146Science, Technology and Innovation Commission of Shenzhen Municipality ZDCYKCX20250901094205007
6 · The paper itself

Abstract

Hydrogel-based sensors have emerged as transformative soft-sensing platforms, featuring tissue-matched compliance, high water content, stimuli responsiveness, and chemical tunability, properties which are unachievable with conventional rigid sensors. Despite substantial advances, the existing reviews focus on individual polymer categories, discrete transduction mechanisms, or targeted standalone applications, failing to establish an integrated pipeline from material design to final sensing performance. This review fills these crucial gaps by systematically correlating polymer chemistry, crosslinking tactics, and fabrication protocols with the selection of transduction mechanisms and resultant sensing performance across biomedical and environmental fields. We conduct a critical assessment of natural and synthetic polymers together with chemical, physical, and hybrid composite crosslinking methodologies. Multiple sensing modalities, including piezoresistive, capacitive, thermogalvanic, electrochemical, colorimetric, ratiometric fluorescence, and piezoionic sensing are elaborated alongside representative quantitative performance parameters. Emerging platforms, including self-powered thermogalvanic sensors, SERS-integrated biosensors, and MXene/MOF composites, are highlighted as underexplored frontiers. In addition, persistent bottlenecks including dehydration-derived signal drift, inferior long-term operational stability, unsatisfactory target selectivity, and obstacles toward large-scale manufacturability are rigorously analyzed. Ultimately, this review constructs a holistic unified framework bridging polymer molecular design, fabrication engineering, signal transduction, and practical end-use applications, laying a clear developmental roadmap for next-generation flexible and smart hydrogel-based sensing systems.

Indexed as

biomedical and environmental monitoringhydrogel-based sensorsnatural polymerssensing mechanismssynthetic polymers

Identifiers

PMID42356981
PMCPMC13307290

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.