ReviewPharmaceuticals (Basel, Switzerland)2026
Targeting Skin Cancer with Natural Bioactive Compounds: From Molecular Mechanisms to Application Strategies.
Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Skin cancer presents a significant global health burden with rising incidence. The side effects of current therapies and the emergence of drug resistance necessitate the exploration of alternative and complementary strategies. Natural products, with their long history of use in treating skin disorders, have emerged as a promising source of novel therapeutic agents. This review comprehensively elucidates the potential efficacy of natural bioactive compounds in both preventing and treating skin cancer. We summarize the molecular mechanisms through which key natural bioactive compounds exert their anti-skin cancer effects, including induction of apoptosis, inhibition of proliferation and metastasis, anti-inflammatory and antioxidant activities, DNA damage repair, and photoprotection. Furthermore, we discuss the biological barriers relevant to skin cancer therapy using natural bioactive compounds and link them to corresponding delivery strategies, while identifying key translational challenges. In conclusion, natural bioactive compounds offer a multi-targeted and synergistic approach against skin carcinogenesis, holding substantial promise as sources of adjuvant therapies and chemopreventive agents to improve patient outcomes.
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Registered trials
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