Evidence map›Paper›PMID 42356458›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

The Complexity of Drug Development: Translational Value and Limitations of Computational ADMET Assays Applied to Approved Anticancer Drugs.

Mirela Nicolov, Adina Octavia Dușe, Elena-Daniela Jurj, Daiana Colibășanu, Adrian Voicu, Claudia Watz, Mirela Voicu, Lucreția Udrescu

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mirela NicolovCenter for Drug Data Analysis, Cheminformatics, and the Internet of Medical Things, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041 Timișoara, Romania.ORCID 0000-0002-8152-5583
Adina Octavia DușeDepartment of Rehabilitation, Physical Medicine and Rheumatology, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041 Timișoara, Romania.ORCID 0009-0004-3300-4910
Elena-Daniela JurjCenter for Drug Data Analysis, Cheminformatics, and the Internet of Medical Things, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041 Timișoara, Romania.
Daiana ColibășanuCenter for Drug Data Analysis, Cheminformatics, and the Internet of Medical Things, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041 Timișoara, Romania.ORCID 0009-0003-2449-3452
Adrian VoicuCenter for Drug Data Analysis, Cheminformatics, and the Internet of Medical Things, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041 Timișoara, Romania.ORCID 0000-0002-9640-3968
Claudia WatzCenter for Drug Data Analysis, Cheminformatics, and the Internet of Medical Things, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041 Timișoara, Romania.ORCID 0000-0002-2498-4732
Mirela VoicuDepartment II-Pharmacology, Physiology and Physiopathology, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041 Timișoara, Romania.ORCID 0000-0002-6505-9367
Lucreția UdrescuCenter for Drug Data Analysis, Cheminformatics, and the Internet of Medical Things, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041 Timișoara, Romania.ORCID 0000-0002-3084-6301

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ADMETanticancer drugsdrug developmentFAF-Drugs4pharmacokineticsSwissADMEtoxicity prediction

Identifiers

PMID42356458
PMCPMC13305401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.