Evidence map›Paper›PMID 42356015›Full record

ReviewJournal of clinical medicine2026

Surgical and Transcatheter Approach of a Failed Mitral Valve Repair: A Comprehensive Review on Selecting the Most Suitable Approach.

Roberto Nerla, Martina Mandas, Gianluca Pillitteri, Elisa Mikus, Niki Bernardoni, Angelo Squeri, Davide Pacini, Carlo Savini, Fausto Castriota

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Roberto NerlaInterventional Cardiology Unit, Maria Cecilia Hospital GVM Care and Research, 48033 Cotignola, Italy.ORCID 0000-0002-9065-3261
Martina MandasInterventional Cardiology Unit, Maria Cecilia Hospital GVM Care and Research, 48033 Cotignola, Italy.
Gianluca PillitteriInterventional Cardiology Unit, Maria Cecilia Hospital GVM Care and Research, 48033 Cotignola, Italy.
Elisa MikusCardiac Surgery Unit, Maria Cecilia Hospital GVM Care and Research, 48033 Cotignola, Italy.ORCID 0000-0003-2892-8700
Niki BernardoniCardiac Surgery Unit, Maria Cecilia Hospital GVM Care and Research, 48033 Cotignola, Italy.
Angelo SqueriInterventional Cardiology Unit, Maria Cecilia Hospital GVM Care and Research, 48033 Cotignola, Italy.ORCID 0000-0001-9115-5443
Davide PaciniCardiac Surgery Unit, Policlinico Sant'Orsola, University of Bologna, 40138 Bologna, Italy.
Carlo SaviniCardiac Surgery Unit, Maria Cecilia Hospital GVM Care and Research, 48033 Cotignola, Italy.ORCID 0000-0003-4197-7486
Fausto CastriotaInterventional Cardiology Unit, Maria Cecilia Hospital GVM Care and Research, 48033 Cotignola, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitral valve regurgitation is the second most common valvular heart disease in Europe, and an estimated 10% of individuals older than 75 years have severe mitral regurgitation. Mitral valve repair is the preferred strategy to treat mitral regurgitation and is associated with better outcomes than mitral valve replacement. Despite the proven efficacy of surgical repair, available data in functional aetiologies reported a non-negligible rate of echocardiographically detected severe mitral regurgitation within ten years of the index procedure, in some cases resulting in redo interventions. Data on the optimal management of patients with failed mitral repair remain limited. The aim of this review is to present the available approaches for treating failed mitral valve repair and to describe criteria for selecting the most appropriate strategy on the basis of the underlying mechanism of repair failure, with respect to possible surgical re-repair and novel transcatheter edge-to-edge repair techniques in the presence of favourable mitral valve anatomies.

Indexed as

heart teammitral regurgitationmitral valve repairmitral valve replacementsurgical mitral valve re-repairtranscatheter edge-to-edge repairtranscatheter mitral valve replacementvalve-in-ringvalve-in-valve

Identifiers

PMID42356015
PMCPMC13301895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.