Evidence map›Paper›PMID 42355879›Full record

ArticleJournal of clinical medicine2026

Stepwise Surgical Management of Persistent Pleural and Parenchymal Sepsis Due to Pan-Resistant Pseudomonas Infection.

Konstantinos Kostopanagiotou, Valentina Karantana, Małgorzata Edyta Wojtyś, Elias Santaintidis, Nikolaos Korodimos, Nektarios I Koufopoulos, Theofanis Nastos, Arkadiusz Waloryszak, Konstantinos Thomas, Periklis Tomos

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In one paragraph

Article in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Konstantinos KostopanagiotouThoracic Surgery Department, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, 12462 Athens, Greece.ORCID 0000-0001-7460-5617
Valentina Karantana4th Department of Internal Medicine, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, 12462 Athens, Greece.
Małgorzata Edyta WojtyśDepartment of Thoracic Surgery and Transplantation, Pomeranian Medical University in Szczecin, Alfreda Sokołowskiego 11, 70-891 Szczecin, Poland.ORCID 0000-0003-0817-1018
Elias SantaintidisThoracic Surgery Department, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, 12462 Athens, Greece.
Nikolaos KorodimosThoracic Surgery Department, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, 12462 Athens, Greece.ORCID 0009-0001-3102-1555
Nektarios I Koufopoulos2nd Department of Pathology, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, 12462 Athens, Greece.ORCID 0000-0001-9502-7916
Theofanis Nastos2nd Department of Pathology, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, 12462 Athens, Greece.ORCID 0009-0008-2455-6966
Arkadiusz WaloryszakStudent Scientific Club of Thoracic Surgery and Transplantation, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.ORCID 0009-0009-3286-3779
Konstantinos Thomas4th Department of Internal Medicine, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, 12462 Athens, Greece.ORCID 0000-0002-7489-7776
Periklis TomosThoracic Surgery Department, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, 12462 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Refractory thoracic infections require targeted antimicrobial combinations, repeated drainage interventions and often staged surgical procedures of varying complexity grades. In necrotizing pneumonia cases, successful treatment is complete removal of destroyed non-functional parenchyma, pleural cavity debridement, and complete pathogen eradication based on culture-based sensitivity-driven antimicrobials. The latter proves challenging in pan-resistant microbial strains where both medical and surgical treatments demonstrate limited effectiveness. We describe a case of persistent thoracic sepsis due to pan-resistant Pseudomonas receiving sequentially thoracoscopic decortication, thoracotomy for lobectomy, and open thoracostomy as the last treatment option to prevent fatal sepsis in view of non-available antibiotics. The immediate source-control effect raised the question of the ideal timing for selecting an aggressive thoracoplastic procedure despite its deforming nature over any other treatment approach.

Indexed as

lung gangrenenecrotizing lung infectionnecrotizing pneumoniapan-resistant Pseudomonaspleural sepsissalvage lobectomythoracoplastythoracoscopic debridement

Identifiers

PMID42355879
PMCPMC13302644

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.