Evidence map›Paper›PMID 42355562›Full record

ArticleLife (Basel, Switzerland)2026

Therapeutic Effects of

Manh Nguyen Dao, Hang Thi Nguyet Pham, Nam Duy Pham, Cuong Viet Vo

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manh Nguyen DaoVietnam-Russia Tropical Science and Technology Research Center, Ha Noi 11307, Vietnam.ORCID 0000-0002-4700-5031
Hang Thi Nguyet PhamDepartment of Pharmacology and Biochemistry, National Institute of Medicinal Materials, Ha Noi 11018, Vietnam.ORCID 0000-0002-2867-5187
Nam Duy PhamVietnam-Russia Tropical Science and Technology Research Center, Ha Noi 11307, Vietnam.
Cuong Viet VoVietnam-Russia Tropical Science and Technology Research Center, Ha Noi 11307, Vietnam.

Funding

Joint Vietnam-Russia Tropical Science and Technology Research Center We don't have Grant Number
6 · The paper itself

Abstract

backgroundOlfactory dysfunction is a pathology associated with viral infections, toxic damage, aging, and neurodegenerative diseases. Damage to the olfactory epithelium impairs olfactory function and related neurological behaviors. This study evaluated the restorative effects of

methodsOlfactory epithelial damage was induced in mice with methimazole, followed by treatment with SBG extract or baicalein. Olfactory and neurobehavioral functions were assessed using odor-finding, novel object recognition (NOR), Morris water maze (MWM), open field (OFT), and elevated plus maze tests (EPM). Histological, immunohistochemical, and

resultsMethimazole induced severe olfactory epithelial damage, impairing olfactory behavior and reducing learning and memory. Treatment with SBG extract and baicalein significantly improved olfactory and cognitive functions. Histological and immunohistochemical analyses confirmed restoration of epithelial structure and olfactory neurons.

conclusionsSBG extract and baicalein promote recovery of olfactory function and improve neurobehavioral outcomes, indicating their potential as therapies for olfactory dysfunction.

Indexed as

baicaleinmethimazole-induced injuryolfactory dysfunctionolfactory epithelial regenerationScutellaria baicalensis Georgi

Identifiers

PMID42355562
PMCPMC13300801

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.