ArticleLife (Basel, Switzerland)2026
Sweet Saliva Trial: Exploratory Evaluation of Salivary Microbiome Responses to Three Thai Desserts.
Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Several studies on diet and microbiome have predominantly focused on the gut microbiome. However, much of the salivary microbiome remains unexplored. This study examined the influence of Thai desserts with varying glycemic indices on the salivary microbiome. A total of 30 healthy adults aged 18-45 years were enrolled in a randomized trial and allocated to one of three intervention groups, with each receiving a culturally specific Thai dessert standardardized to provide 50 g of available carbohydrates: Phetchaburi's Custard Cake (PCC; low-GI, 192 g), Saraburi's Curry Puff (SCP; medium-GI, 98 g), or Lampang's Crispy Rice Cracker (LCRC; high-GI, 68 g). Salivary and dessert microbiome compositions were characterized at baseline and 24 h post-intervention using 16S rRNA sequencing to evaluate bacterial diversity and relative abundance across multiple taxonomic levels.
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