Evidence map›Paper›PMID 42355146›Full record

ArticleMaterials (Basel, Switzerland)2026

Size-Dependent Strength and Reliability of Resin Composite Blocks and Nanoceramics for Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) Restorations.

Fernando Ledesma-Renedo, Eva Paz, Francisco Martínez-Rus, Miguel Ángel Rodríguez-Pérez, Guillermo Pradíes

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Article in Materials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Fernando Ledesma-RenedoAnalysis of Techniques, Material and Instruments Applied to Digital Dentistry and CAD/CAM Procedures Research Group, Department of Conservative and Prosthetic Dentistry, Faculty of Odontology, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-9954-1813
Eva PazInstitute for Research in Technology (IIT), Mechanical Engineering Department, ICAI School of Engineering, Comillas Pontifical University of Madrid, 28015 Madrid, Spain.
Francisco Martínez-RusAnalysis of Techniques, Material and Instruments Applied to Digital Dentistry and CAD/CAM Procedures Research Group, Department of Conservative and Prosthetic Dentistry, Faculty of Odontology, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-0040-1317
Miguel Ángel Rodríguez-PérezCellular Materials Laboratory (CellMat), Condensed Matter Physics Department, Campus Miguel Delibes Science Faculty, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0002-3607-690X
Guillermo PradíesAnalysis of Techniques, Material and Instruments Applied to Digital Dentistry and CAD/CAM Procedures Research Group, Department of Conservative and Prosthetic Dentistry, Faculty of Odontology, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-9716-1385

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical reliability and size-dependent strength behavior remain critical concerns for CAD/CAM restorative materials. This study evaluated resin-based CAD/CAM materials, including resin composite blocks (RCBs) and nanoceramics. The influence of specimen size on flexural strength and the applicability of Weibull-based strength predictions were assessed by comparing experimental and Weibull-predicted values.

methodsTwelve CAD/CAM materials were investigated, including ten resin-based materials and two controls (lithium disilicate ceramic and polymethyl methacrylate). Rectangular specimens (1 × 4 × 14 mm and 1 × 12 × 14 mm) were tested using a three-point bending test. Flexural strength, modulus, and resilience were calculated. Reliability and size dependence were assessed using two-parameter Weibull statistics and effective-volume-based predictions. Data were analyzed using statistical tests selected according to data distribution characteristics (α = 0.05).

resultsRCBs exhibited higher flexural strength, modulus, and resilience than nanoceramics (

conclusionsResin-based CAD/CAM materials demonstrated limited size-dependent behavior compared with brittle ceramics. The reduced agreement between experimental and Weibull-predicted values suggests that effective-volume scaling may have limited applicability for these contemporary materials and should be interpreted cautiously on a material-specific basis.

Indexed as

ceramicscomposite resinscomputer-aided designdental materialsflexural strength

Identifiers

PMID42355146
PMCPMC13303786

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