Evidence map›Paper›PMID 42354977›Full record

ArticleMicroorganisms2026

Biochemical Characterization of LsGajA: A Key Nuclease for Gabija Defense in Lactic Acid Bacteria.

Kexin Li, Yujing Tian, Juyue Luo, Shiyu Ma, Jinhai Huang, Lei Zhang, Deping Hua

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kexin LiSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Yujing TianSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Juyue LuoSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Shiyu MaSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Jinhai HuangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.ORCID 0000-0002-1073-533X
Lei ZhangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Deping HuaSchool of Life Sciences, Tianjin University, Tianjin 300072, China.ORCID 0000-0002-4746-8829

Funding

Tianjin Natural Science Foundation Project 24YFZCSN00300
6 · The paper itself

Abstract

Lactic acid bacteria (LAB), as important probiotics, face challenges in applications from bacteriophage infection and the instability of foreign genetic elements. Although Gabija systems and their GajA nuclease components have been characterized in model bacteria, their distribution, biochemical properties, and defensive functions in LAB remain largely unexplored. Here, we provide the first systematic characterization of a naturally occurring Gabija system from

Indexed as

defense mechanismsGabija systemlactic acid bacteriaLsGajAnuclease

Identifiers

PMID42354977
PMCPMC13304284

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.