Subgingival Microbiota Shifts Following Diode Laser-Activated Indocyanine Green Treatment in Periodontitis: A Pilot 16S rDNA Study.

Dimitra Diakoumopoulou, Aleksandra Slavko, Konstantinos Papadimitriou, Ioannis K Karoussis, Chrysoula Nikolaou, Stylianos Chatzipanagiotou, Anastasios Ioannidis

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Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Dimitra DiakoumopoulouDepartment of Clinical Microbiology, Athens Medical School, Aeginition Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.

Aleksandra SlavkoDepartment of Food Science and Technology, School of Agriculture and Food, University of the Peloponnese, 24100 Kalamata, Greece.ORCID 0009-0003-3104-4831

Konstantinos PapadimitriouLaboratory of Food Quality Control and Hygiene, Department of Food Science and Human Nutrition, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece.ORCID 0000-0002-9614-6543

Ioannis K KaroussisDepartment of Periodontology, School of Dental Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Chrysoula NikolaouDepartment of Clinical Microbiology, Athens Medical School, Aeginition Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.

Stylianos ChatzipanagiotouDepartment of Clinical Microbiology, Athens Medical School, Aeginition Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0002-1251-8355

Anastasios IoannidisDepartment of Clinical Microbiology, Athens Medical School, Aeginition Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0003-1880-7366

Funding

National and Kapodistrian University of Athens 485/03-07-2023/OPN: 9Ρ5Ι46Ψ8Ν2-83Φ

6 · The paper itself

Abstract

Periodontal disease is driven by a dysbiotic subgingival microbiota enriched in anaerobic pathogens, and novel antimicrobial strategies are needed to complement conventional therapy. This pilot study assessed changes in the subgingival microbiota following diode laser-activated indocyanine green-based treatment (EmunDo) using 16S rDNA amplicon sequencing of paired samples collected before and after therapy. Microbiome analysis revealed compositional shifts across all taxonomic levels, with reductions in disease-associated genera including

Indexed as

16S rDNA sequencingEmunDoperiodontal diseaseperiodontal pathogensphotosensitisersubgingival microbiome

Identifiers

PMID42354972

DOI10.3390/microorganisms14061347

PMCPMC13304405

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.