ArticleMicroorganisms2026
Comprehensive Evaluation of Uropathogens' AMR in a Romanian Tertiary Center: Male vs. Female Comparison.
Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
introductionUrinary tract infections (UTIs) represent a growing concern in both clinical practice and public health, affecting hospitalized and outpatient populations across all ages and genders. This study aims to evaluate the prevalence of uropathogens and their antimicrobial resistance profiles in male and female patients comparatively at a tertiary urological center. MATERIALS AND
methodsA retrospective descriptive analysis was conducted, covering three identical 6-month periods-September 1 to February 28-in three consecutive years from 2023 to 2025. The study included 2270 male patients (2270. 57.06%) and 1708 female patients (1708. 42.94%), all with at least one positive urine culture (>10
resultsA higher prevalence of Gram-negative bacteria was observed compared to Gram-positive bacteria in both male (1752; 77.18% vs. 518; 22.82%) and female (1369; 80.15% vs. 339; 19.85%) groups. The most common microorganisms were
conclusionThis study highlights higher resistance rates among Gram-negative bacteria in males to commonly used antibiotics such as fluoroquinolones, trimethoprim/sulfamethoxazole, and β-lactams. Resistance patterns in Gram-positive bacteria remained stable across both populations, with high susceptibility to fosfomycin, nitrofurantoin, linezolid, and carbapenems. Differences between sexes emphasize the need for more detailed analysis of local and sex-specific resistance patterns.
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