Physiology-Mimicking Microfluidic Oxygenator with Good Hemocompatibility for

Yu Tao, Yao Lu, Weijun Zeng, Donggen Xiao, Haixuan Sun

Abstract read

In one paragraph

Article in Micromachines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu TaoSchool of Biomedical Engineering (Suzhou), University of Science and Technology of China, Hefei 230026, China.

Yao LuSchool of Biomedical Engineering (Suzhou), University of Science and Technology of China, Hefei 230026, China.ORCID 0000-0003-3712-4915

Weijun ZengSchool of Biomedical Engineering (Suzhou), University of Science and Technology of China, Hefei 230026, China.

Donggen XiaoSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.

Haixuan SunSchool of Biomedical Engineering (Suzhou), University of Science and Technology of China, Hefei 230026, China.ORCID 0009-0009-6454-7156

Funding

Chinese Academy of Sciences XDB0820101Suzhou Science and Technology Bureau SSD2024012

6 · The paper itself

Abstract

Preterm infants, especially extremely preterm infants under 28 weeks of gestation, face high mortality rates due to respiratory distress resulting from pulmonary immaturity. Conventional mechanical ventilation and extracorporeal membrane oxygenation (ECMO) therapy inevitably cause irreversible lung injury or severe complications, respectively. Here, we developed a microfluidic oxygenator (MO) mimicking the human alveolar-capillary barrier to provide respiratory support for preterm infants. These structures promoted uniform flow distribution, reduced high-shear stress and flow stagnation, and improved gas exchange efficiency. In vitro experiments demonstrated that a single-layer MO raised blood oxygen saturation from 64.7% to 96.5% at 8 mL/min, with a corrected vol% oxygen transfer of 5.24% (52.4 mL O

Indexed as

extracorporeal respiratory supporthemocompatibilitymicrofluidics oxygenatorspreterm infants

Identifiers

PMID42354777

DOI10.3390/mi17060745

PMCPMC13302908

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.