Evidence map›Paper›PMID 42354531›Full record

ArticleHealthcare (Basel, Switzerland)2026

Collaborative Practice in Oral Nutritional Supplement Provision: The Critical Role of Pharmacists in the Patient Journey.

Željko Krznarić, Darija Vranešić Bender, Dina Ljubas Kelečić, Nikica Daraboš, Ivan Radoš, Ana Soldo

Abstract read
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Article in Healthcare (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Željko KrznarićUnit of Clinical Nutrition, Department of Internal Medicine, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.ORCID 0000-0003-3758-4540
Darija Vranešić BenderUnit of Clinical Nutrition, Department of Internal Medicine, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.
Dina Ljubas KelečićUnit of Clinical Nutrition, Department of Internal Medicine, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.
Nikica DarabošDepartment of Physiotherapy, University North, Ulica 104. Brigade 3, 42000 Varaždin, Croatia.
Ivan RadošMedical Nutrition Industry Coordination-CEA, Radnička Cesta 37a, 10000 Zagreb, Croatia.
Ana SoldoCroatian Chamber of Pharmacists, Martićeva Ulica 27, 10000 Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesDisease-related malnutrition affects millions of patients worldwide. Nutrition support therapy (NST), namely oral nutritional supplements (ONSs), serve as a cornerstone therapeutic intervention. However, treatment effectiveness depends not only on an appropriate prescription but also on patient acceptance and adherence. This study evaluates the provision pathway of ONSs within a co-payment healthcare system, focusing on patient acceptance patterns, barriers to adherence, and the critical yet underexplored role of pharmacist-patient interactions in determining treatment outcomes.

methodsA cross-sectional observational study was conducted across 100 Croatian community pharmacies during September-October 2025. Pharmacists prospectively documented 973 patient encounters involving ONS prescriptions requiring co-payment using real-time patient record forms. Data captured patient demographics, diagnoses, prescription patterns, prior knowledge of co-payment requirements, acceptance responses, and pharmacist-assessed reasons for refusal.

resultsWhile 65% of all patients knew about co-payment requirements in advance, 51% of first-time users arrived uninformed, leading to dramatically different acceptance patterns (93% immediate acceptance when informed versus 33% when uninformed,

conclusionsThese findings suggest that the pharmacy dispensing encounter is an important decision point in the ONS care pathway, where insufficient preparation and coordination may be associated with suboptimal treatment outcomes among vulnerable patient populations. Improved prescriber-patient communication about co-payment and clinical rationale, pharmacist education in disease-specific nutrition and ONS counseling, and structured communication protocols between prescribers and pharmacists represent areas that may warrant further attention and evaluation.

Indexed as

collaborative practiceco-payment barriersdisease-related malnutrition (DRM)healthcare communicationnutritional therapyoral nutritional supplements (ONSs)patient adherencepharmacist role

Identifiers

PMID42354531
PMCPMC13300124

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.