Evidence map›Paper›PMID 42354110›Full record

ArticleFoods (Basel, Switzerland)2026

Valorization of Brewing By-Products for Sustainable Active Material.

Luciana B Malbos, Paula Garcia-Oliveira, Irene T Seoane, Jesus Simal-Gandara, Liliana B Manfredi, Viviana P Cyras, Lucía Cassani

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luciana B MalbosInstituto de Investigaciones en Ciencia y Tecnología de Materiales (INTEMA), Facultad de Ingeniería, Universidad Nacional de Mar del Plata-Consejo de Investigaciones Científicas y Técnicas (CONICET), Mar del Plata 7600, Argentina.ORCID 0009-0000-7502-6940
Paula Garcia-OliveiraUniversidade de Vigo, Departamento de Química Analítica y Alimentaria, Facultad de Ciencias, 32004 Ourense, Spain.ORCID 0000-0003-4058-3709
Irene T SeoaneInstituto de Investigaciones en Ciencia y Tecnología de Materiales (INTEMA), Facultad de Ingeniería, Universidad Nacional de Mar del Plata-Consejo de Investigaciones Científicas y Técnicas (CONICET), Mar del Plata 7600, Argentina.ORCID 0000-0002-7231-3984
Jesus Simal-GandaraUniversidade de Vigo, Departamento de Química Analítica y Alimentaria, Facultad de Ciencias, 32004 Ourense, Spain.ORCID 0000-0001-9215-9737
Liliana B ManfrediInstituto de Investigaciones en Ciencia y Tecnología de Materiales (INTEMA), Facultad de Ingeniería, Universidad Nacional de Mar del Plata-Consejo de Investigaciones Científicas y Técnicas (CONICET), Mar del Plata 7600, Argentina.ORCID 0000-0002-0492-0416
Viviana P CyrasInstituto de Investigaciones en Ciencia y Tecnología de Materiales (INTEMA), Facultad de Ingeniería, Universidad Nacional de Mar del Plata-Consejo de Investigaciones Científicas y Técnicas (CONICET), Mar del Plata 7600, Argentina.ORCID 0000-0002-4769-0198
Lucía CassaniUniversidade de Vigo, Departamento de Química Analítica y Alimentaria, Facultad de Ciencias, 32004 Ourense, Spain.ORCID 0000-0001-6597-9334

Funding

Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo 323RT0142
6 · The paper itself

Abstract

Brewer's spent grain (BSG), the main by-product of the brewing industry, is an abundant lignocellulosic residue that remains underused. In this study, antioxidant-rich extracts were obtained from BSG using pressurized liquid extraction (PLE) and subsequently incorporated into thermoplastic starch (TPS) films for sustainable food packaging applications. The phenolic profile analysis revealed 13 compounds, with caffeic acid and its hexoside as the most abundant. Extraction conditions were optimized using response surface methodology (RSM) to maximize yield and total phenolic content, showing that temperature had a significant positive effect. The selected extract had a total phenolic content of 3.19 mg/g dw and exhibited notable antioxidant activity. It was then incorporated into the polymer matrix, and the resulting films were analyzed for their structural, thermal, and antioxidant properties. The incorporation of BSG extracts improved the film antioxidant activity. Additionally, the release of phenolic compounds was evaluated and successfully described using a diffusion model based on Fick's law, which allowed the calculation of a diffusion coefficient D = 2.63 × 10

Indexed as

active packagingbrewer’s spent grainpressurized liquid extractionresponse surface methodologystarch

Identifiers

PMID42354110
PMCPMC13298428

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.