Evidence map›Paper›PMID 42353887›Full record

ArticleChildren (Basel, Switzerland)2026

Anakinra in a Preterm Infant with Bronchopulmonary Dysplasia: A Case Report.

Simona Fattore, Chiara Tirone, Alessandro Perri, Francesca Paola Fusco, Simonetta Frezza, Milena Tana, Donato Rigante, Davide De Tomaso, Nicoletta Menzella, Alessandra Lio and 6 more

Abstract readCase Reports
In one paragraph

Article in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Simona FattoreDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-2991-2068
Chiara TironeDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-9191-4219
Alessandro PerriDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-8914-8639
Francesca Paola FuscoDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Simonetta FrezzaDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Milena TanaDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Donato RiganteDepartment of Women and Child Health Sciences, Child Health Area, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy.ORCID 0000-0001-7032-7779
Davide De TomasoDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Nicoletta MenzellaDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0009-0009-8023-167X
Alessandra LioDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Francesca SerraoDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-7115-1469
Stefano NobileDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-5304-1485
Andrea PirasU.O.C. Farmacia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Silvia BaroniUnit of Chemistry, Biochemistry and Molecular Biology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0009-0009-8528-7533
Simonetta CostaNeonatology and Neonatal Intensive Care Unit, Policlinico Casilino, 00169 Rome, Italy.ORCID 0000-0003-0980-5297
Giovanni VentoDivision of Neonatology, Department of Women and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0003-3121-9569

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchopulmonary dysplasia (BPD) remains a major complication of extreme prematurity, driven in part by persistent inflammation. Interleukin (IL)-1-mediated signaling plays a central role in sustaining lung injury, making IL-1 blockade a potential therapeutic target. Evidence on the use of anakinra, a recombinant IL-1 receptor antagonist, in neonatal BPD is still limited. We report the case of a female preterm infant (28

Indexed as

anakinrabronchopulmonary dysplasiainnovative biotechnologiesinterleukin-1neonatespersonalized medicine

Identifiers

PMID42353887
PMCPMC13297449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.