Evidence map›Paper›PMID 42353590›Full record

ArticleCurrent issues in molecular biology2026

Presence of Tuft Cells Expressing Hematopoietic Prostaglandin D Synthase in Acinar-to-Ductal Metaplasia in Human Obstructive Pancreatitis.

Kenta Hosomi, Mitsuaki Ishida, Kensuke Nakanishi, Kohei Taniguchi, Jun Arima, Atsushi Tomioka, Mitsuhiro Asakuma, Sang-Woong Lee, Ko Fujimori, Yoshinobu Hirose

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kenta HosomiDepartment of Pathobiochemistry, Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, 4-20-1, Nasahara, Takatsuki City 569-1094, Osaka, Japan.
Mitsuaki IshidaDepartment of Pathology, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki City 569-8686, Osaka, Japan.
Kensuke NakanishiDepartment of Pathology, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki City 569-8686, Osaka, Japan.
Kohei TaniguchiCenter for Medical Research & Development, Division of Translational Research, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki City 569-8686, Osaka, Japan.ORCID 0000-0003-0648-1370
Jun ArimaDepartment of General and Gastroenterological Surgery, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki City 569-8686, Osaka, Japan.
Atsushi TomiokaDepartment of General and Gastroenterological Surgery, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki City 569-8686, Osaka, Japan.
Mitsuhiro AsakumaDepartment of General and Gastroenterological Surgery, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki City 569-8686, Osaka, Japan.
Sang-Woong LeeDepartment of General and Gastroenterological Surgery, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki City 569-8686, Osaka, Japan.ORCID 0000-0002-2540-0655
Ko FujimoriDepartment of Pathobiochemistry, Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, 4-20-1, Nasahara, Takatsuki City 569-1094, Osaka, Japan.ORCID 0000-0002-2506-0769
Yoshinobu HiroseDepartment of Pathology, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki City 569-8686, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acinar-to-ductal metaplasia (ADM)-a process involving the dedifferentiation or transdifferentiation of pancreatic acinar cells-is recognized as an initial event in pancreatic tumorigenesis. Studies in mouse models have revealed that tuft cells, which are chemosensory epithelial cells, appear in ADM following tissue injury, and tuft cell-produced prostaglandin (PG) D

Indexed as

acinar-to-ductal metaplasiaobstructive pancreatitispancreasprostaglandin D2tuft cell

Identifiers

PMID42353590
PMCPMC13297796

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.