Evidence map›Paper›PMID 42353573›Full record

ArticleCurrent issues in molecular biology2026

Resistance Training Complements Anti-TNF Therapy in DSS-Induced Colitis by Improving Skeletal Muscle Inflammatory and Mitochondrial Gene Signatures.

Ya Zhu, Xiaochun Zhang, Chao Jin, Heying Jin

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ya ZhuThe Second Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210017, China.
Xiaochun ZhangThe Second Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210017, China.ORCID 0009-0000-3644-5333
Chao JinThe Second Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210017, China.
Heying JinThe Second Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210017, China.

Funding

Jiangsu Province Science and Technology Department BE2023786Jiangsu Provincial Commission of Health and Family Planning MS2023047Jiangsu Provincial Commission of Health and Family Planning ZD202421
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is associated with skeletal muscle loss and mitochondrial dysfunction, which may compromise therapeutic responsiveness. We investigated whether progressive resistance training could improve muscle oxidative phosphorylation gene expression and enhance the efficacy of anti-TNF-α therapy (infliximab) in a dextran sulfate sodium (DSS)-induced colitis mouse model. Male C57BL/6 mice with subacute DSS-induced colitis were assigned to control, DSS, DSS + resistance training, DSS + anti-TNF-α, and DSS + resistance training + anti-TNF-α groups (

Indexed as

anti-TNF-αinflammatory bowel diseasemitochondriaoxidative phosphorylationresistance trainingtranscriptomics

Identifiers

PMID42353573
PMCPMC13298207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.