Evidence map›Paper›PMID 42353572›Full record

ArticleCurrent issues in molecular biology2026

Tomato Polyphenols Protect Human Red Blood Cells from Mercury-Induced Oxidative Stress and Phosphatidylserine Exposure.

Claudia Moriello, Nicola Alessio, Rosario Finamore, Chiara De Rosa, Chiara Schiraldi, Caterina Manna, Stefania D'Angelo, Pasquale Perrone

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Flavonoids: Hemorheological effects and mechanisms of action.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Claudia MorielloDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0001-9975-4918
Nicola AlessioDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-5019-2130
Rosario FinamoreDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Chiara De RosaSchool of Medicine and Surgery, Department of Clinical Medicine, Surger University of Naples Federico II, 80131 Naples, Italy.
Chiara SchiraldiDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-1066-843X
Caterina MannaDepartment of Precision Medicine, School of Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0001-9603-0017
Stefania D'AngeloDepartment of Medical, Movement, and Wellbeing Sciences, Parthenope University of Naples, 80133 Naples, Italy.ORCID 0000-0001-7585-5052
Pasquale PerroneDepartment of Psychology and Health Sciences, Pegaso Telematic University, 80143 Naples, Italy.ORCID 0000-0002-5627-0267

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress plays a central role in the development of cardiovascular diseases (CVDs) and is strongly influenced by environmental toxicants such as heavy metals. Mercury (Hg) is a well-known pro-oxidant agent capable of disrupting cellular redox homeostasis, promoting reactive oxygen species (ROS) generation, and inducing structural and functional alterations in circulating blood cells. In particular, erythrocytes (RBC) are highly susceptible to oxidative damage due to their continuous exposure to oxygen and limited antioxidant repair mechanisms. In this study, we investigated the protective effects of polyphenolic extracts obtained from two tomato (

Indexed as

cardiovascular riskmercury toxicityoxidative stressphosphatidylserine externalizationreactive oxygen speciesred blood cellstomato polyphenols

Identifiers

PMID42353572
PMCPMC13297506

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.