Evidence map›Paper›PMID 42353563›Full record

ReviewCurrent issues in molecular biology2026

Research Progress on Coronary Artery Injury and Myocardial Ischemia in Multisystem Inflammatory Syndrome in Children.

Jirong Liu, Nanyan Mao, Yaru Cui, Yiyao Bao, Chao Tang

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jirong LiuNational Clinical Research Center for Children and Adolescents' Health and Diseases, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, China.
Nanyan MaoNational Clinical Research Center for Children and Adolescents' Health and Diseases, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, China.
Yaru CuiNational Clinical Research Center for Children and Adolescents' Health and Diseases, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, China.
Yiyao BaoNational Clinical Research Center for Children and Adolescents' Health and Diseases, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, China.ORCID 0009-0003-2185-2122
Chao TangNational Clinical Research Center for Children and Adolescents' Health and Diseases, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, China.ORCID 0000-0002-5072-5849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a severe systemic inflammatory complication triggered by prior SARS-CoV-2 infection. It predominantly affects the cardiovascular system, and coronary artery injury, myocardial dysfunction, and myocardial ischemia are closely associated with disease severity and clinical outcomes. This article reviews the immunopathological characteristics and clinical manifestations of MIS-C-related coronary artery lesions, including coronary artery dilation and aneurysm formation, as well as the key pathophysiological mechanisms leading to myocardial ischemia. Based on recent clinical and translational research, we summarize current approaches to diagnosis, risk stratification, acute medical management, and long-term follow-up strategies. By synthesizing updated evidence, this review aims to provide theoretical support and practical clinical guidance for the early identification, timely intervention, and optimized management of affected children, ultimately improving their long-term cardiovascular prognosis.

Indexed as

coronary artery aneurysmcoronary artery injuryinflammatory stormmultisystem inflammatory syndrome in children (MIS-C)myocardial ischemia

Identifiers

PMID42353563
PMCPMC13297741

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.