Evidence map›Paper›PMID 42353446›Full record

ArticleAnimals : an open access journal from MDPI2026

Notoginsenoside R1 Inhibits Porcine Deltacoronavirus Infection In Vitro by Restoring SERCA2-Mediated Calcium Homeostasis.

Jialu Zhang, Yuqian Liu, Wenzhe Liu, Zhouyuan Wang, Hanlu Wang, Xuejing Xia, Lianci Peng, Tingting Chen, Rendong Fang

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jialu ZhangJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China.ORCID 0000-0001-7237-5942
Yuqian LiuJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China.
Wenzhe LiuJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China.
Zhouyuan WangKunming Hemeihua Feed Limited Company, Kunming 682100, China.
Hanlu WangJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China.
Xuejing XiaJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China.
Lianci PengJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China.
Tingting ChenJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China.ORCID 0009-0005-8224-5232
Rendong FangJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China.

Funding

National Natural Science Foundation of China 32473027National Natural Science Foundation of China 32503119the Chongqing Modern Agricultural Industry Technology System CQMAITS202512the Co-construction Project of Fuling Academy of Southwest University FLYJY202506the Fundamental Research Funds for the Central Universities SWU-KQ25021the Natural Science Foundation of Chongqing CSTB2025NSCQ-GPX0489Yunnan Province Science and Technology Department 202405AF140106
6 · The paper itself

Abstract

Porcine coronavirus is one of the prevalent enteric coronaviruses in pigs, causing watery diarrhea and even death in suckling piglets and resulting in giant losses to the pig industry. However, effective antiviral strategies against PDCoV remain limited. Notoginsenoside R1 (NG-R1), a saponin extracted from

Indexed as

cellular calcium ionsendoplasmic reticulumNotoginsenoside R1porcine deltacoronavirus

Identifiers

PMID42353446
PMCPMC13295528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.