Evidence map›Paper›PMID 42353307›Full record

ArticleInternational journal of molecular sciences2026

DNA-Mimic Antirestriction Proteins ArdA Could Regulate Gene Expression in

Anna A Utkina, Anna A Kudryavtseva, Rodion V Berezov, Kamilla V Mekhantseva, Olga E Melkina, Sergey M Rastorguev, Mikhail A Skutel, Artem B Isaev, Ilya V Manukhov

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna A UtkinaMoscow Center for Advanced Studies, 123592 Moscow, Russia.
Anna A KudryavtsevaMoscow Center for Advanced Studies, 123592 Moscow, Russia.
Rodion V BerezovMoscow Center for Advanced Studies, 123592 Moscow, Russia.
Kamilla V MekhantsevaMoscow Center for Advanced Studies, 123592 Moscow, Russia.ORCID 0000-0003-3403-9395
Olga E MelkinaKurchatov Complex of Genetic Research, NRC 'Kurchatov Institute', Kurchatov Square, 1, 123182 Moscow, Russia.ORCID 0000-0002-7507-4827
Sergey M RastorguevPirogov Russian National Research Medical University, 117513 Moscow, Russia.ORCID 0000-0002-0095-0255
Mikhail A SkutelCenter for Bio- and Medical Technologies, 121205 Moscow, Russia.
Artem B IsaevCenter for Bio- and Medical Technologies, 121205 Moscow, Russia.ORCID 0000-0002-9593-2745
Ilya V ManukhovMoscow Center for Advanced Studies, 123592 Moscow, Russia.

Funding

Ministry of Science and Higher Education 075-03-2025-662, project FSMG-2025-0003Research Center Kurchatov Institute State AssignmentRussian Foundation for Basic Research № 22-14-00124-ПRussian Science Foundation project 24-74-00024Russian Science Foundation project 24-74-10089
6 · The paper itself

Abstract

Antirestriction proteins protect mobile genetic elements from the host's restriction-modification systems. Here, we investigated the ability of ArdA and ArdB antirestriction proteins to regulate gene expression in an engineered

Indexed as

DNA-Binding ProteinsEscherichia coliEscherichia coli K12Escherichia coli ProteinsGene Expression Regulation, BacterialDNA, BacterialPlasmidsPromoter Regions, GeneticProtein BindingDNA, BacterialDNA-Binding ProteinsEscherichia coli ProteinsantirestrictionArdAArdBbiosensorrestriction

Identifiers

PMID42353307
PMCPMC13300388

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.