Evidence map›Paper›PMID 42353292›Full record

ArticleInternational journal of molecular sciences2026

MicroRNA Biogenesis Pathway Gene Variants Are Associated with Prostate Cancer Susceptibility.

Irina Gilyazova, Yanina Timasheva, Elizaveta Ivanova, Galiya Gimalova, Adel Izmailov, Gulshat Abdeeva, Murat Dzaubermezov, Zhanna Balkhiyarova, Inga Prokopenko, Valentin Pavlov and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Irina GilyazovaInstitute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, 450054 Ufa, Russia.ORCID 0000-0001-9499-5632
Yanina TimashevaInstitute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, 450054 Ufa, Russia.
Elizaveta IvanovaLaboratory of Population and Medical Genetics, Ufa University of Science and Technology, 450076 Ufa, Russia.
Galiya GimalovaInstitute of Urology and Clinical Oncology, Department of Medical Genetics and Fundamental Medicine, Bashkir State Medical University, 450008 Ufa, Russia.ORCID 0000-0003-0779-4678
Adel IzmailovInstitute of Urology and Clinical Oncology, Department of Medical Genetics and Fundamental Medicine, Bashkir State Medical University, 450008 Ufa, Russia.
Gulshat AbdeevaInstitute of Urology and Clinical Oncology, Department of Medical Genetics and Fundamental Medicine, Bashkir State Medical University, 450008 Ufa, Russia.
Murat DzaubermezovLaboratory of Population and Medical Genetics, Ufa University of Science and Technology, 450076 Ufa, Russia.ORCID 0000-0003-1570-3174
Zhanna BalkhiyarovaDepartment of Clinical & Experimental Medicine, University of Surrey, Guildford GU2 7XH, UK.ORCID 0000-0003-3553-7126
Inga ProkopenkoDepartment of Clinical & Experimental Medicine, University of Surrey, Guildford GU2 7XH, UK.ORCID 0000-0003-1624-7457
Valentin PavlovInstitute of Urology and Clinical Oncology, Department of Medical Genetics and Fundamental Medicine, Bashkir State Medical University, 450008 Ufa, Russia.ORCID 0000-0003-2125-4897
Elza KhusnutdinovaInstitute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, 450054 Ufa, Russia.

Funding

The Ministry of Education and Science of the Russian Federation Bashkir State Medical University Strategic Academic Leadership Program (PRIORITY-2030)
6 · The paper itself

Abstract

Prostate cancer (PrC) is one of the most common malignancies among men worldwide. However, the contribution of genetic variation in microRNA (miRNA) biogenesis pathway genes to PrC susceptibility remains poorly characterized in many ethnically diverse populations. We conducted a case-control study involving 532 PrC patients and 550 controls from the Volga-Ural region of Eurasia to evaluate the association of twenty-one single nucleotide polymorphisms (SNPs) with PrC risk using single-variant and polygenic approaches. Association analyses identified rs595055 in the

Indexed as

Argonaute ProteinsEukaryotic Initiation FactorsGenetic Predisposition to DiseaseMicroRNAsPolymorphism, Single NucleotideProstatic NeoplasmsAgedCase-Control StudiesGenetic Risk ScoreHumansMaleMiddle AgedAGO1 protein, humanArgonaute ProteinsEukaryotic Initiation FactorsMicroRNAsgenetic risk scoremiRNAprostate cancer

Identifiers

PMID42353292
PMCPMC13299046

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.