Evidence map›Paper›PMID 42353263›Full record

ArticleInternational journal of molecular sciences2026

Evaluation of CXCL12 Diagnostic Performance in Tick-Borne Encephalitis and Other Central Nervous System Infections.

Paulina Świętoń, Jakub Słoń, Anna Moniuszko-Malinowska, Ewelina Kruszewska, Sambor Grygorczuk

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paulina ŚwiętońStudent Scientific Society at the Department of Infectious Diseases and Neuroinfections, Medical University of Bialystok, ul. Żurawia 14, 15-540 Białystok, Poland.ORCID 0009-0004-7595-2820
Jakub SłońStudent Scientific Society at the Department of Infectious Diseases and Neuroinfections, Medical University of Bialystok, ul. Żurawia 14, 15-540 Białystok, Poland.
Anna Moniuszko-MalinowskaDepartment of Infectious Diseases and Neuroinfections, Medical University of Bialystok, ul. Żurawia 14, 15-540 Białystok, Poland.
Ewelina KruszewskaDepartment of Infectious Diseases and Neuroinfections, Medical University of Bialystok, ul. Żurawia 14, 15-540 Białystok, Poland.ORCID 0000-0002-6015-2351
Sambor GrygorczukDepartment of Infectious Diseases and Neuroinfections, Medical University of Bialystok, ul. Żurawia 14, 15-540 Białystok, Poland.ORCID 0000-0002-8462-3285

Funding

National Science Centre 2018/31/B/NZ6/02744
6 · The paper itself

Abstract

CXCL12 is a chemokine acting via CXCR4 that plays a key role in inflammatory processes by regulating leukocyte migration and immune responses, making it an important focus of research in neuroinfections. In this study, the CXCL12 chemokine was evaluated as a potential diagnostic marker of different neuroinfections with particular emphasis on tick-borne encephalitis (TBE). A group of 214 patients with confirmed meningitis and/or encephalitis was included and divided according to etiology into TBE, aseptic meningitis, neuroborreliosis, and purulent meningitis. CXCL12 concentration and other inflammatory parameters were measured in cerebrospinal fluid (CSF). CXCL12 levels were compared with those of controls (

Indexed as

Central Nervous System InfectionsChemokine CXCL12Encephalitis, Tick-BorneAdultAgedBiomarkersFemaleHumansLeukocytosisMaleMeningitis, AsepticMiddle AgedBiomarkersChemokine CXCL12CXCL12 protein, humanchemokine CXCL12neuroinfectionpleocytosistick-borne encephalitis

Identifiers

PMID42353263
PMCPMC13299119

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.