Evidence map›Paper›PMID 42353224›Full record

ReviewInternational journal of molecular sciences2026

Potential Health Benefits of Bee Bread from Stingless Bees on Reproductive Health: A Review.

Nurul Ain Kamar Bashah, Adila A Hamid, Farah Hanan Fathihah Jaffar, Mohd Zulkifli Mustafa, Siti Hajar Adam, Siti Sarah Mohamad Zaid, Wan Iryani Wan Ismail, Muhammad Adib Dwi Tamma Putra, Mohd Helmy Mokhtar

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nurul Ain Kamar BashahDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia.ORCID 0000-0003-1014-6428
Adila A HamidDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia.
Farah Hanan Fathihah JaffarDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia.ORCID 0000-0001-7645-3805
Mohd Zulkifli MustafaDepartment of Neuroscience, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kota Bharu 16150, Malaysia.ORCID 0000-0002-8140-8184
Siti Hajar AdamPreclinical Department, Faculty of Medicine & Defence Health, Universiti Pertahanan Nasional Malaysia, Kuala Lumpur 57000, Malaysia.ORCID 0000-0003-3014-6169
Siti Sarah Mohamad ZaidDepartment of Environment, Faculty of Forestry and Environment, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0002-9615-7170
Wan Iryani Wan IsmailCell Signaling and Biotechnology Research Group (CeSBTech), Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, Kuala Terengganu 21030, Malaysia.ORCID 0000-0001-8069-2278
Muhammad Adib Dwi Tamma PutraDepartment of Physical Medicine and Rehabilitation, Faculty of Medicine, University of Sriwijaya Palembang, Kota Palembang 30128, Indonesia.ORCID 0009-0007-7679-394X
Mohd Helmy MokhtarDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia.ORCID 0000-0002-7801-6358

Funding

Universiti Kebangsaan Malaysia GUP-2024-034
6 · The paper itself

Abstract

Bees are social insects belonging to the Apidae family, which includes stingless bees, honeybees, and related groups. Their ability to produce various products, such as bee bread, bee pollen, propolis, beeswax, and royal jelly, has attracted scientific interest due to their nutritional composition, biological activities, and potential therapeutic value. Bee bread is a fermented mixture of pollen, honey, and salivary bee enzymes, rich in bioactive compounds with potential benefits for reproductive health and other biological activities. However, bee bread remains one of the least explored bee products in relation to reproductive health. This narrative review summarises the potential health benefits of bee bread from stingless bees for male and female reproductive function. Evidence from animal studies shows that bee bread has promising effects on reproductive function, possibly through its antioxidant properties, support of spermatogenesis and steroidogenesis, improvement of pregnancy outcomes, enhancement of ovarian function, regulation of metabolism, and modulation of inflammatory activity. Findings from animal studies suggest potential benefits for both male and female reproductive health. However, well-designed randomised controlled trials are needed to evaluate its efficacy, optimal dosage, safety profile, and long-term effects on reproductive outcomes in both males and females.

Indexed as

HoneyReproductionReproductive HealthAnimalsAntioxidantsBeesFemaleHumansMalePollenPropolisRoyal JellySpermatogenesisAntioxidantsPropolisRoyal Jellyantioxidantbee breadovarian functionreproductive healthspermatogenesissteroidogenesis

Identifiers

PMID42353224
PMCPMC13299326

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.