Evidence map›Paper›PMID 42353130›Full record

ArticleInternational journal of molecular sciences2026

Candidate Faecal microRNAs as Non-Invasive Biomarkers for Bovine Paratuberculosis in

Martina Torricelli, Laura Madeo, Anna Fratto, Andrea Felici, Linda Petrucci, Carla Sebastiani, Marco Ermini, Massimo Biagetti, Marcella Ciullo, Matteo Ricchi and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Martina TorricelliIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" (IZSUM), 06126 Perugia, Italy.ORCID 0000-0001-6409-3582
Laura MadeoIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" (IZSUM), 06126 Perugia, Italy.
Anna FrattoIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" (IZSUM), 06126 Perugia, Italy.ORCID 0000-0003-1974-9700
Andrea FeliciIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" (IZSUM), 06126 Perugia, Italy.ORCID 0000-0002-1306-6629
Linda PetrucciIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" (IZSUM), 06126 Perugia, Italy.
Carla SebastianiIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" (IZSUM), 06126 Perugia, Italy.
Marco ErminiAzienda Sanitaria Territoriale Macerata, Servizio Veterinario di Sanità Animale, 62100 Macerata, Italy.
Massimo BiagettiIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" (IZSUM), 06126 Perugia, Italy.ORCID 0000-0003-4744-3389
Marcella CiulloIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" (IZSUM), 06126 Perugia, Italy.ORCID 0000-0003-1995-1984
Matteo RicchiWOAH Reference Laboratory for Paratuberculosis, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia-Romagna "Bruno Ubertini" (IZSLER), Gariga Podenzano, 29027 Piacenza, Italy.ORCID 0000-0002-4923-0216
Katia CappelliDipartimento di Scienze Veterinarie, Università degli Studi di Perugia, 06126 Perugia, Italy.ORCID 0000-0002-3141-771X
Piera MazzoneIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" (IZSUM), 06126 Perugia, Italy.ORCID 0000-0002-8526-9468

Funding

Ministero della Salute IZSUM 06/2021 RC and IZSUM 04/2024 RC
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs that play a crucial role in the post-transcriptional regulation of gene expression. Since miRNAs modulate host immune responses, they represent promising molecular biomarkers of paratuberculosis (PTB), particularly during early or subclinical stages, when conventional diagnostic tests may lack sensitivity. In this context, faecal miRNAs could provide valuable insights into intestinal immune responses and mucosal damage associated with

Indexed as

Cattle DiseasesFecesMicroRNAsParatuberculosisAnimalsBiomarkersCattleFemaleGene Expression ProfilingMycobacterium avium subsp. paratuberculosisBiomarkersMicroRNAsfaecal miRNAgene expression profilinghost–pathogen interactionMarchigiana beef cattlenon-invasive biomarkersparatuberculosisTaqMan RT-qPCR

Identifiers

PMID42353130
PMCPMC13300290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.