Chronic Exposure to

Imane Lejri, Amandine Grimm, Pascal Trempat, Stephanie Chanut, Naoual Boujedaini, Anne Eckert

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Imane LejriNeurobiology Laboratory for Brain Aging and Mental Health, Transfaculty Research Platform, Molecular & Cognitive Neuroscience, University of Basel, CH-4002 Basel, Switzerland.

Amandine GrimmNeurobiology Laboratory for Brain Aging and Mental Health, Transfaculty Research Platform, Molecular & Cognitive Neuroscience, University of Basel, CH-4002 Basel, Switzerland.ORCID 0000-0003-3323-1756

Pascal TrempatLaboratoire Boiron, 2 Avenue de l'Ouest Lyonnais, 69510 Messimy, France.ORCID 0000-0003-1050-9663

Stephanie ChanutLaboratoire Boiron, 2 Avenue de l'Ouest Lyonnais, 69510 Messimy, France.

Naoual BoujedainiDépartement de Recherche Clinique, Institut de Cancérologie de Lorraine-ICL, 6 Avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy Cedex, France.ORCID 0000-0002-4011-5967

Anne EckertNeurobiology Laboratory for Brain Aging and Mental Health, Transfaculty Research Platform, Molecular & Cognitive Neuroscience, University of Basel, CH-4002 Basel, Switzerland.ORCID 0000-0002-9341-3669

Funding

Boiron (France) This investigator-initiated research was funded by Laboratoires Boiron (France). The funding source had no role in data analysis, interpretation, or the decision to submit the manuscript for publication.

6 · The paper itself

Abstract

Stress-related psychiatric disorders are frequently associated with impaired mitochondrial function, altered neuronal energy metabolism, and reduced neuroplasticity. Intracellular pathways such as PI3K/Akt and mTOR play central roles in regulating mitochondrial bioenergetics and neuronal structural adaptation.

Indexed as

Energy MetabolismGelsemiumMitochondriaNeuronal OutgrowthNeuronsProto-Oncogene Proteins c-aktSignal TransductionTOR Serine-Threonine KinasesCell Line, TumorCell SurvivalHumansOxidative StressPhosphorylationReactive Oxygen SpeciesMTOR protein, humanProto-Oncogene Proteins c-aktReactive Oxygen SpeciesTOR Serine-Threonine KinasesAkt/mTOR signalingGelsemium preparationsmitochondrial bioenergeticsneurite outgrowthneuroprotection

Identifiers

PMID42353128

DOI10.3390/ijms27125409

PMCPMC13300635

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.