Evidence map›Paper›PMID 42353070›Full record

ArticleInternational journal of molecular sciences2026

Cross-Compartment Virome Profiling in Human Immunodeficiency Virus Infection and Substance Use Disorder Reveals Brain-CSF-Periphery Discordance and Hepatitis B Virus in Central Nervous System.

Xin Dang, Barbara A Hanson, Melissa Lopez, Janet Miller, Igor J Koralnik

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xin DangDavee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Barbara A HansonDavee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-1060-9448
Melissa LopezDavee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Janet MillerNorthwestern Medicine, Chicago, IL 60611, USA.
Igor J KoralnikDavee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0001-6836-1468

Funding

Contribution of the Virome to HIV/AIDS pathogenesisDP1DA048493 · NIDA · RUSH UNIVERSITY MEDICAL CENTER · PI KORALNIK, IGOR J. · 2019 to 2024
$4.3M
NIDA NIH HHS DP1 DA048493
6 · The paper itself

Abstract

The diversity and abundance of the brain virome is an active field of investigation. However, how the brain virome relates to the presence of viruses outside of the nervous system remains unclear. The rationale for this study is that analyses across multiple biologically linked compartments within the same individuals provide an important opportunity to evaluate virome discordance and viral burden. To characterize viral prevalence and burden across anatomical compartments, we applied the targeted viral enrichment method ViroFind to matched postmortem brain (

Indexed as

BrainCentral Nervous SystemHepatitis BHepatitis B virusHIV InfectionsSubstance-Related DisordersViromeAdultFemaleHumansMaleViral Loadbraincerebrospinal fluidmetagenomic sequencingViroFindviruses

Identifiers

PMID42353070
PMCPMC13300052

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.