Evidence map›Paper›PMID 42352980›Full record

ArticleInternational journal of molecular sciences2026

Family-Based Study Reveals

Luiza Côrtes, Ana Beatriz Rodrigues, Sara Martoreli Silveira, Julieta M Ramírez-Mejía, Carine Spenassatto Dreyer, Mads M Aagaard, Geysson Javier Fernandez, Ademar Lopes, José Carlos S Trindade Filho, Silvia Regina Rogatto

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luiza CôrtesBotucatu Medical School Hospital (HCFMB), São Paulo State University-UNESP, Botucatu 18618-687, SP, Brazil.
Ana Beatriz RodriguesBotucatu Medical School Hospital (HCFMB), São Paulo State University-UNESP, Botucatu 18618-687, SP, Brazil.
Sara Martoreli SilveiraTeaching Department, Universidade Nove de Julho (UNINOVE), São Paulo 01504-001, SP, Brazil.ORCID 0009-0002-0868-856X
Julieta M Ramírez-MejíaLaboratorio de Biología y Control de Enfermedades Infecciosas (BCEI), Sede de Investigación Universitaria (SIU), Facultad de Ciencias Exactas y Naturales, Instituto de Biología, Universidad de Antioquia, Medellín 050010, Colombia.ORCID 0000-0002-4787-7147
Carine Spenassatto DreyerBotucatu Medical School Hospital (HCFMB), São Paulo State University-UNESP, Botucatu 18618-687, SP, Brazil.ORCID 0000-0003-3353-3500
Mads M AagaardClinical Genetics Department, University Hospital of Southern Denmark, 7100 Vejle, Denmark.ORCID 0000-0003-4742-7047
Geysson Javier FernandezLaboratorio de Biología y Control de Enfermedades Infecciosas (BCEI), Sede de Investigación Universitaria (SIU), Facultad de Ciencias Exactas y Naturales, Instituto de Biología, Universidad de Antioquia, Medellín 050010, Colombia.ORCID 0000-0002-8493-1587
Ademar LopesDepartment of Pelvic Surgery, A.C. Camargo Cancer Center, São Paulo 01509-001, SP, Brazil.
José Carlos S Trindade FilhoBotucatu Medical School Hospital (HCFMB), São Paulo State University-UNESP, Botucatu 18618-687, SP, Brazil.
Silvia Regina RogattoBotucatu Medical School Hospital (HCFMB), São Paulo State University-UNESP, Botucatu 18618-687, SP, Brazil.ORCID 0000-0003-4637-5687

Funding

National Council for Scientific and Technological Development 573589/08-9São Paulo Research Foundation 2008/57887-9São Paulo Research Foundation 2024/04461-7
6 · The paper itself

Abstract

Testicular germ cell tumor (TGCT) is a common tumor type in young men. Family history of TGCT and its presence in twins support the involvement of inherited genetic factors. Germline exome sequencing was performed on monozygotic twins with TGCT and their parents. The twins presented compound heterozygous variants in

Indexed as

3',5'-Cyclic-GMP PhosphodiesterasesGenetic Predisposition to DiseaseNeoplasms, Germ Cell and EmbryonalRNA, Long NoncodingTesticular NeoplasmsExome SequencingHumansMalePedigreePolymorphism, Single Nucleotide3',5'-Cyclic-GMP PhosphodiesterasesPDE11A protein, humanRNA, Long Noncodinggerm cell tumorPDE11APDE11A-AS1testicular cancerwhole exome sequencing

Identifiers

PMID42352980
PMCPMC13300246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.