Evidence map›Paper›PMID 42352953›Full record

ArticleInternational journal of molecular sciences2026

Plasma Lipidomics Identify Pathways Linked to Acute Lung Injury in a Porcine One-Lung Ventilation Surgery Model.

Simone C da Silva Rosa, Evan Gauvin, Dagem Chernet, Jay Kormish, Catherine Giffin, Martha Hinton, Shyamala Dakshinamurti, Ruth Graham, Christopher D Pascoe, Amir Ravandi and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Simone C da Silva RosaBiology of Breathing Research Theme, the Children's Hospital Research Institute of Manitoba, Winnipeg, MB R3E 3P4, Canada.ORCID 0000-0002-3732-3781
Evan GauvinUndergraduate Medical Education (UGME), Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada.
Dagem ChernetBiology of Breathing Research Theme, the Children's Hospital Research Institute of Manitoba, Winnipeg, MB R3E 3P4, Canada.ORCID 0000-0001-6001-7013
Jay KormishBiology of Breathing Research Theme, the Children's Hospital Research Institute of Manitoba, Winnipeg, MB R3E 3P4, Canada.ORCID 0000-0003-2974-8533
Catherine GiffinUndergraduate Medical Education (UGME), Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada.
Martha HintonUndergraduate Medical Education (UGME), Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada.
Shyamala DakshinamurtiDepartment of Physiology and Pathophysiology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.ORCID 0000-0001-7279-5226
Ruth GrahamDepartment of Anesthesiology, Perioperative and Pain Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0Z2, Canada.
Christopher D PascoeBiology of Breathing Research Theme, the Children's Hospital Research Institute of Manitoba, Winnipeg, MB R3E 3P4, Canada.ORCID 0000-0002-5229-9927
Amir RavandiDepartment of Physiology and Pathophysiology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.ORCID 0000-0001-6663-1225
Biniam KidaneBiology of Breathing Research Theme, the Children's Hospital Research Institute of Manitoba, Winnipeg, MB R3E 3P4, Canada.ORCID 0000-0002-2982-2505

Funding

2024 GFT Surgery Grant F327961Health Sciences Centre Foundation Operating Grant R510837Hoeschen Memorial Award 2024 F328279
6 · The paper itself

Abstract

One-lung ventilation (OLV) is performed during lung surgeries by ventilating a single lung, while collapsing the operative lung to provide surgical exposure within the thoracic cavity. While a lung-protective ventilation strategy is recommended during OLV, increasing the fraction of inspired oxygen (FiO

Indexed as

Acute Lung InjuryLipidomicsLipidsOne-Lung VentilationAnimalsDisease Models, AnimalLungSwineLipidsacute lung injuryinflammationlipidomicsone-lung-ventilationplasmaporcinepostoperative complications

Identifiers

PMID42352953
PMCPMC13299324

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.