Evidence map›Paper›PMID 42352899›Full record

ArticleInternational journal of molecular sciences2026

Identification of Candidate mRNA and miRNA Molecules Associated with Tuberculosis Through Preliminary Analysis and Validation Using Clinical Samples.

Yanxi Ma, Yujuan Fu, Jiahui Li, Guangyu Xu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yanxi MaCollege of Pharmacy, Beihua University, Jilin 132013, China.
Yujuan FuCollege of Pharmacy, Beihua University, Jilin 132013, China.
Jiahui LiCollege of Pharmacy, Beihua University, Jilin 132013, China.
Guangyu XuCollege of Pharmacy, Beihua University, Jilin 132013, China.ORCID 0000-0002-5802-4457

Funding

National Natural Science Foundation of China 81973371
6 · The paper itself

Abstract

Tuberculosis (TB) remains a major global public health burden. This study aimed to identify differentially expressed messenger RNAs (mRNAs) and circulating microRNAs (miRNAs) associated with TB and to validate their potential roles in the disease. We performed RNA sequencing (RNA-Seq) on peripheral blood samples from 10 patients with active pulmonary TB and 10 healthy controls, using peripheral blood mononuclear cells (PBMCs) for mRNA sequencing and plasma for miRNA sequencing. Given the exploratory nature of the plasma miRNA data and the limitations of the

Indexed as

MicroRNAsRNA, MessengerTuberculosisTuberculosis, PulmonaryAdultFemaleForkhead Transcription FactorsGene Expression ProfilingGene Expression RegulationHumansLeukocytes, MononuclearMaleMiddle AgedSequence Analysis, RNATumor Suppressor Protein p53Forkhead Transcription FactorsMicroRNAsRNA, MessengerTumor Suppressor Protein p53candidate moleculesmicroRNAsRT-qPCR validationtranscriptome sequencingtuberculosis

Identifiers

PMID42352899
PMCPMC13299930

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.