Evidence map›Paper›PMID 42352588›Full record

ArticleBrain sciences2026

Early-Term Effect of Bilateral Sequential Cochlear Implantation on the Audiovestibular Function of Paediatric Patients: A Prospective Pilot Study.

Federica Di Berardino, Marco Pozzi, Anna Maria Gasbarre, Valeria Castelli, Cinzia Lazzarini, Giorgio Lilli, Diego Zanetti, Valerio Maria Di Pasquale Fiasca

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Article in Brain sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Federica Di BerardinoDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0001-7514-5624
Marco PozziDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Anna Maria GasbarreDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Valeria CastelliDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Cinzia LazzariniDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Giorgio LilliDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Diego ZanettiDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Valerio Maria Di Pasquale FiascaDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesSequential bilateral cochlear implantation is being increasingly considered in paediatric patients with bilateral profound hearing loss, particularly when the contralateral ear shows limited residual hearing or poor speech discrimination. Although auditory benefits of a second cochlear implant (CI2) have been reported, concerns remain regarding possible vestibular impairment after surgery. This study aimed to provide a preliminary prospective evaluation of early audiological and vestibular outcomes in children undergoing sequential bilateral cochlear implantation and to explore whether the age at implantation or the inter-implant interval influenced longitudinal trajectories.

methodsTen children with prelingual bilateral profound sensorineural hearing loss who underwent sequential bilateral cochlear implantation were prospectively enrolled. Assessments were performed at baseline and during follow-up up to 12 months after CI2 activation. The audiological evaluation included pure-tone audiometry, speech recognition in quiet with CI2 alone and bilaterally, and speech-in-noise testing in frontal and lateralised configurations. The vestibular evaluation included static stabilometry and video head impulse testing. Patient-reported outcomes were assessed using the speech, spatial and qualities of hearing scale for children. Longitudinal changes were analysed using mixed-effects models with false discovery rate correction.

resultsUnilateral speech recognition with CI2 improved significantly over time, with median word recognition increasing from 0% at 3 months to 60% at 12 months (

conclusionsSequential bilateral cochlear implantation was associated with early auditory benefit, particularly for CI2 unilateral performance and speech perception in noise, without evidence of major short-term vestibular deterioration.

Indexed as

balancechildrensequential cochlear implantvestibular function

Identifiers

PMID42352588
PMCPMC13296405

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