ArticleBrain sciences2026
CT Texture Analysis of Acute Ischemic Stroke: Prediction of Hemorrhagic Transformation After Thrombolysis.
Article in Brain sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundHemorrhagic transformation is a major complication after thrombolysis in acute ischemic stroke, and its risk assessment based on baseline non-contrast CT (NCCT) remains limited. This study aims to evaluate the role of CT-based texture analysis of the infarcted region on baseline NCCT in characterizing tissue vulnerability to hemorrhagic transformation.
methodsThis retrospective single-center study included 50 patients with supratentorial acute ischemic stroke treated with thrombolysis. All patients underwent baseline NCCT and follow-up CT at 24 h and were divided into those with hemorrhagic transformation (
resultsGray-level and run-length non-uniformity features were significantly lower in patients with hemorrhagic transformation (
conclusionsCT-based texture analysis of baseline NCCT may provide additional quantitative information associated with subsequent hemorrhagic transformation. However, given the small sample size, single-center design and absence of external validation, these findings should be interpreted as exploratory and hypothesis-generating.
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