Evidence map›Paper›PMID 42352540›Full record

ReviewCancers2026

Risk Factors for Catastrophic Health Events in Head and Neck Cancer: A Scoping Review to Inform Risk Prediction.

Christabel Oghinan, Deema ElRufaei, Frederick Dun-Dery, Diane Lorenzetti, Sasha Mallya, Andrea S Fung, Shamir P Chandarana, T Wayne Matthews, Tracy Hyndman, Joseph C Dort and 1 more

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christabel OghinanDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Deema ElRufaeiDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Frederick Dun-DeryDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.ORCID 0000-0003-2791-0103
Diane LorenzettiDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.ORCID 0000-0001-8423-3458
Sasha MallyaDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N2, Canada.
Andrea S FungDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N2, Canada.
Shamir P ChandaranaDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N2, Canada.ORCID 0000-0001-6612-4717
T Wayne MatthewsDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N2, Canada.ORCID 0000-0002-7596-6470
Tracy HyndmanDepartment of Surgery, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 2T9, Canada.
Joseph C DortDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.ORCID 0000-0002-0858-187X
Rui FuDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.ORCID 0000-0002-0577-2830

Funding

Alberta Cancer Foundation Arthur J.E. Child Foundation Innovation Catalyst GrantCIHR Undergraduate Summer Studentship AwardUniversity of Calgary Arnie Charbonneau Cancer Institute EDIA (Equity, Diversity, Inclusion, and Accessibility) Summer Studentship Award
6 · The paper itself

Abstract

BACKGROUND/

objectivesHead and neck cancer (HNC) is associated with unique risks of catastrophic health events throughout the care continuum. This scoping review evaluated distinct domains of catastrophic health events in HNC and the associated risk factors to inform the development of risk prediction models.

methodsFive electronic databases were searched to identify peer-reviewed journal articles published from 2015 to 2025. Eligible studies were primary observational studies involving adults (≥18) with HNC that reported a catastrophic (or similar term) health event and assessed the associated risk factors using multivariable regression modelling.

resultsFifty-six studies involving 941,329 patients with HNC were included. Half (

conclusionsRisk prediction models in HNC should always include variables of comorbidity. The varied measurability of risk factors requires strategic efforts when developing prediction algorithms for different domains of catastrophic health events.

Indexed as

adverse eventscatastrophic health eventshead and neck cancerrisk factorsrisk prediction

Identifiers

PMID42352540
PMCPMC13296962

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.