Evidence map›Paper›PMID 42352535›Full record

ArticleCancers2026

Metabolomics Approach Identifies Predictive Serum Markers for Hepatocellular Carcinogenesis Following Hepatitis C Virus Elimination.

Takeshi Chida, Satoshi Sakai, Masahiko Ito, Kazumasa Sekihara, Kazuyoshi Ohta, Masahiro Matsushita, Gou Murohisa, Fujito Kageyama, Yuzo Sasada, Tatsuki Oyaizu and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Takeshi ChidaSecond Department of Internal Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Shizuoka, Japan.ORCID 0000-0002-6389-0528
Satoshi SakaiDepartment of Molecular Biology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Shizuoka, Japan.
Masahiko ItoDepartment of Microbiology and Immunology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Shizuoka, Japan.ORCID 0000-0001-7020-7312
Kazumasa SekiharaDepartment of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1 Chome-3-2 Kagamiyama, Higashihiroshima 734-8553, Hiroshima, Japan.ORCID 0009-0001-3795-4604
Kazuyoshi OhtaSecond Department of Internal Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Shizuoka, Japan.ORCID 0000-0002-4690-8706
Masahiro MatsushitaDepartment of Gastroenterology, Shimada General Medical Center, 1200-5 Noda, Shimada 427-8501, Shizuoka, Japan.
Gou MurohisaDepartment of Hepatology, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Hamamatsu 430-8558, Shizuoka, Japan.
Fujito KageyamaDepartment of Hepatology, Hamamatsu Medical Center, 328 Tomitsuka, Hamamatsu 432-8580, Shizuoka, Japan.
Yuzo SasadaDepartment of Hepatology, Iwata City Hospital, 512-3 Okubo, Iwata 438-8550, Shizuoka, Japan.
Tatsuki OyaizuDepartment of Gastroenterology, Shizuoka City Shizuoka Hospital, 10-93 Otemachi, Shizuoka 420-8630, Shizuoka, Japan.
Minoru TsugikiMinoru Medical Clinic, Mishima 1784-1, Hamamatsu 430-0853, Shizuoka, Japan.
Katsutoshi TamakoshiTamakoshi Clinic, Maruzuka 262-1, Hamamatsu 435-0046, Shizuoka, Japan.
Tomomi OkuboDivision of Gastroenterology, Department of Internal Medicine, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai 270-1694, Chiba, Japan.
Sachiyo YoshioThe Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa 272-8516, Chiba, Japan.
Masanori AtsukawaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Nippon Medical School, 1-1-5 Sendagi, Tokyo 113-8602, Japan.ORCID 0000-0003-3374-7111
Akihito TsubotaProject Research Units, Research Center for Medical Science, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Tokyo 105-8461, Japan.ORCID 0000-0001-6860-0326
Yasuhito TanakaDepartment of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8555, Kumamoto, Japan.ORCID 0000-0002-2473-6966
Tatsuya KantoThe Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa 272-8516, Chiba, Japan.
Toshiyuki OjimaDepartment of Community Health and Preventive Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Shizuoka, Japan.ORCID 0000-0001-6888-0698
Kazuhito KawataSecond Department of Internal Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Shizuoka, Japan.ORCID 0000-0002-4986-8578
Takafumi SudaSecond Department of Internal Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Shizuoka, Japan.
Tetsuro SuzukiDepartment of Microbiology and Immunology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Shizuoka, Japan.ORCID 0000-0002-3754-789X

Funding

Hamamatsu University School of Medicine N.AJapan Agency for Medical Research and Development JP22fk0210066h0103Ministry of Education, Culture, Sports, Science and Technology JP18H02661
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

hepatitis C virus (HCV)hepatocellular carcinoma (HCC)metabolomicssustained virological response (SVR)

Identifiers

PMID42352535
PMCPMC13297395

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.